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Reduced Sensitivity to Immediate Reward during Decision-Making in Older than Younger Adults
We examined whether older adults differ from younger adults in the degree to which they favor immediate over delayed rewards during decision-making. To examine the neural correlates of age-related differences in delay discounting we acquired functional MR images while participants made decisions bet...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3359996/ https://www.ncbi.nlm.nih.gov/pubmed/22655032 http://dx.doi.org/10.1371/journal.pone.0036953 |
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author | Eppinger, Ben Nystrom, Leigh E. Cohen, Jonathan D. |
author_facet | Eppinger, Ben Nystrom, Leigh E. Cohen, Jonathan D. |
author_sort | Eppinger, Ben |
collection | PubMed |
description | We examined whether older adults differ from younger adults in the degree to which they favor immediate over delayed rewards during decision-making. To examine the neural correlates of age-related differences in delay discounting we acquired functional MR images while participants made decisions between smaller but sooner and larger but later monetary rewards. The behavioral results show age-related reductions in delay discounting. Less impulsive decision-making in older adults was associated with lower ventral striatal activations to immediate reward. Furthermore, older adults showed an overall higher percentage of delayed choices and reduced activity in the dorsal striatum than younger adults. This points to a reduced reward sensitivity of the dorsal striatum in older adults. Taken together, our findings indicate that less impulsive decision-making in older adults is due to a reduced sensitivity of striatal areas to reward. These age-related changes in reward sensitivity may result from transformations in dopaminergic neuromodulation with age. |
format | Online Article Text |
id | pubmed-3359996 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-33599962012-05-31 Reduced Sensitivity to Immediate Reward during Decision-Making in Older than Younger Adults Eppinger, Ben Nystrom, Leigh E. Cohen, Jonathan D. PLoS One Research Article We examined whether older adults differ from younger adults in the degree to which they favor immediate over delayed rewards during decision-making. To examine the neural correlates of age-related differences in delay discounting we acquired functional MR images while participants made decisions between smaller but sooner and larger but later monetary rewards. The behavioral results show age-related reductions in delay discounting. Less impulsive decision-making in older adults was associated with lower ventral striatal activations to immediate reward. Furthermore, older adults showed an overall higher percentage of delayed choices and reduced activity in the dorsal striatum than younger adults. This points to a reduced reward sensitivity of the dorsal striatum in older adults. Taken together, our findings indicate that less impulsive decision-making in older adults is due to a reduced sensitivity of striatal areas to reward. These age-related changes in reward sensitivity may result from transformations in dopaminergic neuromodulation with age. Public Library of Science 2012-05-24 /pmc/articles/PMC3359996/ /pubmed/22655032 http://dx.doi.org/10.1371/journal.pone.0036953 Text en Eppinger et al. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited. |
spellingShingle | Research Article Eppinger, Ben Nystrom, Leigh E. Cohen, Jonathan D. Reduced Sensitivity to Immediate Reward during Decision-Making in Older than Younger Adults |
title | Reduced Sensitivity to Immediate Reward during Decision-Making in Older than Younger Adults |
title_full | Reduced Sensitivity to Immediate Reward during Decision-Making in Older than Younger Adults |
title_fullStr | Reduced Sensitivity to Immediate Reward during Decision-Making in Older than Younger Adults |
title_full_unstemmed | Reduced Sensitivity to Immediate Reward during Decision-Making in Older than Younger Adults |
title_short | Reduced Sensitivity to Immediate Reward during Decision-Making in Older than Younger Adults |
title_sort | reduced sensitivity to immediate reward during decision-making in older than younger adults |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3359996/ https://www.ncbi.nlm.nih.gov/pubmed/22655032 http://dx.doi.org/10.1371/journal.pone.0036953 |
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