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The ter Mutation in the Rat Dnd1 Gene Initiates Gonadal Teratomas and Infertility in Both Genders
A spontaneous mutation leading to the formation of congenital ovarian and testicular tumors was detected in the WKY/Ztm rat strain. The histological evaluation revealed derivatives from all three germ layers, thereby identifying these tumors as teratomas. Teratocarcinogenesis was accompanied by infe...
Autores principales: | Northrup, Emily, Zschemisch, Nils-Holger, Eisenblätter, Regina, Glage, Silke, Wedekind, Dirk, Cuppen, Edwin, Dorsch, Martina, Hedrich, Hans-Jürgen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3360017/ https://www.ncbi.nlm.nih.gov/pubmed/22655094 http://dx.doi.org/10.1371/journal.pone.0038001 |
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