Cargando…

Identification and Characterisation of a Novel Acylpeptide Hydrolase from Sulfolobus Solfataricus: Structural and Functional Insights

A novel acylpeptide hydrolase, named APEH-3(Ss), was isolated from the hypertermophilic archaeon Sulfolobus solfataricus. APEH is a member of the prolyl oligopeptidase family which catalyzes the removal of acetylated amino acid residues from the N terminus of oligopeptides. The purified enzyme shows...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gogliettino, Marta, Balestrieri, Marco, Cocca, Ennio, Mucerino, Sabrina, Rossi, Mose, Petrillo, Mauro, Mazzella, Emanuela, Palmieri, Gianna
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3360023/ https://www.ncbi.nlm.nih.gov/pubmed/22655081 http://dx.doi.org/10.1371/journal.pone.0037921

Ejemplares similares

A New Pepstatin-Insensitive Thermopsin-Like Protease Overproduced in Peptide-Rich Cultures of Sulfolobus solfataricus
por: Gogliettino, Marta, et al.
Publicado: (2014)

Differential Distribution and Activity Profile of Acylpeptide Hydrolase in the Rat Seminiferous Epithelium
por: Covarrubias, Alejandra A., et al.
Publicado: (2022)

Acylpeptide Hydrolase Inhibition as Targeted Strategy to Induce Proteasomal Down-Regulation
por: Palmieri, Gianna, et al.
Publicado: (2011)

Structural analysis of the Sulfolobus solfataricus MCM protein N-terminal domain(†)
por: Liu, Wei, et al.
Publicado: (2008)

RedOx Status, Proteasome and APEH: Insights into Anticancer Mechanisms of t10,c12-Conjugated Linoleic Acid Isomer on A375 Melanoma Cells
por: Bergamo, Paolo, et al.
Publicado: (2013)

A New APEH Cluster with Antioxidant Functions in the Antarctic Hemoglobinless Icefish Chionodraco hamatus
por: Riccio, Alessia, et al.
Publicado: (2015)

APEH Inhibition Affects Osteosarcoma Cell Viability via Downregulation of the Proteasome
por: Palumbo, Rosanna, et al.
Publicado: (2016)

Uncommon functional properties of the first piscine 26S proteasome from the Antarctic notothenioid Trematomus bernacchii
por: Gogliettino, Marta, et al.
Publicado: (2016)

A spreadable, non-integrative and high copy number shuttle vector for Sulfolobus solfataricus based on the genetic element pSSVx from Sulfolobus islandicus
por: Aucelli, Tiziana, et al.
Publicado: (2006)

Selective degradation of reverse gyrase and DNA fragmentation induced by alkylating agent in the archaeon Sulfolobus solfataricus
por: Valenti, Anna, et al.
Publicado: (2006)

Structure of the heterotrimeric PCNA from Sulfolobus solfataricus
por: Williams, Gareth J., et al.
Publicado: (2006)

“Hot standards” for the thermoacidophilic archaeon Sulfolobus solfataricus
por: Zaparty, Melanie, et al.
Publicado: (2009)

Molecular Dynamics Simulations of Acylpeptide Hydrolase Bound to Chlorpyrifosmethyl Oxon and Dichlorvos
por: Jin, Hanyong, et al.
Publicado: (2015)

Internalization of Erythrocyte Acylpeptide Hydrolase Is Required for Asexual Replication of Plasmodium falciparum
por: Elahi, Rubayet, et al.
Publicado: (2019)

Identification and Characterization of Small RNAs in the Hyperthermophilic Archaeon Sulfolobus solfataricus
por: Xu, Ning, et al.
Publicado: (2012)

Replication termination and chromosome dimer resolution in the archaeon Sulfolobus solfataricus
por: Duggin, Iain G, et al.
Publicado: (2011)

The bindosome is a structural component of the Sulfolobus solfataricus cell envelope
por: Zolghadr, Benham, et al.
Publicado: (2011)

Membrane Association and Catabolite Repression of the Sulfolobus solfataricus α-Amylase
por: Soo, Edith, et al.
Publicado: (2015)

Harnessing hyperthermostable lactonase from Sulfolobus solfataricus for biotechnological applications
por: Rémy, Benjamin, et al.
Publicado: (2016)

TopA, the Sulfolobus solfataricus topoisomerase III, is a decatenase
por: Bizard, Anna H, et al.
Publicado: (2018)

A strategy to recover a poor-quality ligase product
por: Del Prete, Sonia, et al.
Publicado: (2023)

A new versatile peroxidase with extremophilic traits over-produced in MicroTom cell cultures
por: Gogliettino, Marta, et al.
Publicado: (2023)

CRISPR-mediated targeted mRNA degradation in the archaeon Sulfolobus solfataricus
por: Zebec, Ziga, et al.
Publicado: (2014)

Antisense regulation by transposon-derived RNAs in the hyperthermophilic archaeon Sulfolobus solfataricus
por: Märtens, Birgit, et al.
Publicado: (2013)

Modification of translation factor aIF5A from Sulfolobus solfataricus
por: Bassani, F., et al.
Publicado: (2018)

The Carbon Switch at the Level of Pyruvate and Phosphoenolpyruvate in Sulfolobus solfataricus P2
por: Haferkamp, Patrick, et al.
Publicado: (2019)

Systems biology of the modified branched Entner-Doudoroff pathway in Sulfolobus solfataricus
por: Figueiredo, Ana Sofia, et al.
Publicado: (2017)

Crystal structure of the translation recovery factor Trf from Sulfolobus solfataricus
por: Kaiser, Marco, et al.
Publicado: (2019)

Insight into the cellular involvement of the two reverse gyrases from the hyperthermophilic archaeon Sulfolobus solfataricus
por: Couturier, Mohea, et al.
Publicado: (2014)

Unusual Antioxidant Properties of 26S Proteasome Isolated from Cold-Adapted Organisms
por: Gogliettino, Marta, et al.
Publicado: (2017)

Bypass of Aflatoxin B(1) Adducts by the Sulfolobus solfataricus DNA Polymerase IV
por: Banerjee, Surajit, et al.
Publicado: (2011)

Genome-Scale Reconstruction and Analysis of the Metabolic Network in the Hyperthermophilic Archaeon Sulfolobus Solfataricus
por: Ulas, Thomas, et al.
Publicado: (2012)

Complete Genome Sequence of Sulfolobus solfataricus Strain 98/2 and Evolved Derivatives
por: McCarthy, Samuel, et al.
Publicado: (2015)

Optimization of an In Vitro Transcription/Translation System Based on Sulfolobus solfataricus Cell Lysate
por: Lo Gullo, Giada, et al.
Publicado: (2019)

Interplay between Alba and Cren7 Regulates Chromatin Compaction in Sulfolobus solfataricus
por: Cajili, Marc Kenneth M., et al.
Publicado: (2022)

Oxidized Substrates of APEH as a Tool to Study the Endoprotease Activity of the Enzyme
por: Sandomenico, Annamaria, et al.
Publicado: (2021)

In Sulfolobus solfataricus, the Poly(ADP-Ribose) Polymerase-Like Thermoprotein Is a Multifunctional Enzyme
por: De Maio, Anna, et al.
Publicado: (2020)

Structural–Functional Relationship of the Ribonucleolytic Activity of aIF5A from Sulfolobus solfataricus
por: Romagnoli, Alice, et al.
Publicado: (2022)

The Bactericidal Activity of Protein Extracts from Loranthus europaeus Berries: A Natural Resource of Bioactive Compounds
por: Ambrosio, Rosa Luisa, et al.
Publicado: (2020)

Biomonitoring of blood cholinesterases and acylpeptide hydrolase activities in rural inhabitants exposed to pesticides in the Coquimbo Region of Chile
por: Ramírez-Santana, Muriel, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_m4106ioao5d84tttm9ivs631dg