Cargando…
Shifting the Paradigm: The Putative Mitochondrial Protein ABCB6 Resides in the Lysosomes of Cells and in the Plasma Membrane of Erythrocytes
ABCB6, a member of the adenosine triphosphate–binding cassette (ABC) transporter family, has been proposed to be responsible for the mitochondrial uptake of porphyrins. Here we show that ABCB6 is a glycoprotein present in the membrane of mature erythrocytes and in exosomes released from reticulocyte...
Autores principales: | Kiss, Katalin, Brozik, Anna, Kucsma, Nora, Toth, Alexandra, Gera, Melinda, Berry, Laurence, Vallentin, Alice, Vial, Henri, Vidal, Michel, Szakacs, Gergely |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3360040/ https://www.ncbi.nlm.nih.gov/pubmed/22655043 http://dx.doi.org/10.1371/journal.pone.0037378 |
Ejemplares similares
-
Role of the N-terminal transmembrane domain in the endo-lysosomal targeting and function of the human ABCB6 protein
por: Kiss, Katalin, et al.
Publicado: (2015) -
Screening the Expression of ABCB6 in Erythrocytes Reveals an Unexpectedly High Frequency of Lan Mutations in Healthy Individuals
por: Koszarska, Magdalena, et al.
Publicado: (2014) -
The human ABCB6 protein is the functional homologue of HMT-1 proteins mediating cadmium detoxification
por: Rakvács, Zsófia, et al.
Publicado: (2019) -
A new fluorescent dye accumulation assay for parallel measurements of the ABCG2, ABCB1 and ABCC1 multidrug transporter functions
por: Szabó, Edit, et al.
Publicado: (2018) -
A Novel Mathematical Model Describing Adaptive Cellular Drug Metabolism and Toxicity in the Chemoimmune System
por: Tóth, Attila, et al.
Publicado: (2015)