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Full-Exon Pyrosequencing Screening of BRCA Germline Mutations in Mexican Women with Inherited Breast and Ovarian Cancer
Hereditary breast cancer comprises 10% of all breast cancers. The most prevalent genes causing this pathology are BRCA1 and BRCA2 (breast cancer early onset 1 and 2), which also predispose to other cancers. Despite the outstanding relevance of genetic screening of BRCA deleterious variants in patien...
Autores principales: | Vaca-Paniagua, Felipe, Alvarez-Gomez, Rosa María, Fragoso-Ontiveros, Verónica, Vidal-Millan, Silvia, Herrera, Luis Alonso, Cantú, David, Bargallo-Rocha, Enrique, Mohar, Alejandro, López-Camarillo, César, Pérez-Plasencia, Carlos |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3360054/ https://www.ncbi.nlm.nih.gov/pubmed/22655046 http://dx.doi.org/10.1371/journal.pone.0037432 |
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