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Activation of BK(Ca) Channels in Zoledronic Acid-Induced Apoptosis of MDA-MB-231 Breast Cancer Cells

BACKGROUND: Zoledronic acid, one of the most potent nitrogen-containing biphosphonates, has been demonstrated to have direct anti-tumor and anti-metastatic properties in breast cancer in vitro and in vivo. In particular, tumor-cell apoptosis has been recognized to play an important role in the treat...

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Detalles Bibliográficos
Autores principales: Ma, Yu-Guang, Liu, Wen-Chao, Dong, Shuo, Du, Cheng, Wang, Xiao-Jun, Li, Jin-Sheng, Xie, Xiao-Ping, Wu, Li, Ma, Da-Chang, Yu, Zhi-Bin, Xie, Man-Jiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3360057/
https://www.ncbi.nlm.nih.gov/pubmed/22655048
http://dx.doi.org/10.1371/journal.pone.0037451