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Assessment of circadian rhythms in humans: comparison of real-time fibroblast reporter imaging with plasma melatonin
We compared the period of the rhythm of plasma melatonin, driven by the hypothalamic circadian pacemaker, to in vitro periodicity in cultured peripheral fibroblasts to assess the effects on these rhythms of a polymorphism of PER3 (rs57875989), which is associated with sleep timing. In vitro circadia...
Autores principales: | Hasan, Sibah, Santhi, Nayantara, Lazar, Alpar S., Slak, Ana, Lo, June, von Schantz, Malcolm, Archer, Simon N., Johnston, Jonathan D., Dijk, Derk-Jan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Federation of American Societies for Experimental Biology
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3360144/ https://www.ncbi.nlm.nih.gov/pubmed/22371527 http://dx.doi.org/10.1096/fj.11-201699 |
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