Inhibition of Intestinal Bile Acid Transporter Slc10a2 Improves Triglyceride Metabolism and Normalizes Elevated Plasma Glucose Levels in Mice

Interruption of the enterohepatic circulation of bile acids increases cholesterol catabolism, thereby stimulating hepatic cholesterol synthesis from acetate. We hypothesized that such treatment should lower the hepatic acetate pool which may alter triglyceride and glucose metabolism. We explored thi...

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Detalles Bibliográficos
Autores principales: Lundåsen, Thomas, Andersson, Eva-Marie, Snaith, Michael, Lindmark, Helena, Lundberg, Johanna, Östlund-Lindqvist, Ann-Margret, Angelin, Bo, Rudling, Mats
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3360597/
https://www.ncbi.nlm.nih.gov/pubmed/22662222
http://dx.doi.org/10.1371/journal.pone.0037787

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3360597/
https://www.ncbi.nlm.nih.gov/pubmed/22662222
http://dx.doi.org/10.1371/journal.pone.0037787

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