Cargando…

Cardiac Explant-Derived Cells Are Regulated by Notch-Modulated Mesenchymal Transition

BACKGROUND: Progenitor cell therapy is emerging as a novel treatment for heart failure. However the molecular mechanisms regulating the generation of cardiac progenitor cells is not fully understood. We hypothesized that cardiac progenitor cells are generated from cardiac explant via a process simil...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zakharova, Liudmila, Nural-Guvener, Hikmet, Gaballa, Mohamed A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3360598/ https://www.ncbi.nlm.nih.gov/pubmed/22662227 http://dx.doi.org/10.1371/journal.pone.0037800

Ejemplares similares

Chronic Heart Failure Is Associated With Transforming Growth Factor Beta‐Dependent Yield and Functional Decline in Atrial Explant‐Derived c‐Kit+ Cells
por: Zakharova, Liudmila, et al.
Publicado: (2013)

Anti-Fibrotic Effects of Class I HDAC Inhibitor, Mocetinostat Is Associated with IL-6/Stat3 Signaling in Ischemic Heart Failure
por: Nural-Guvener, Hikmet, et al.
Publicado: (2015)

HDAC class I inhibitor, Mocetinostat, reverses cardiac fibrosis in heart failure and diminishes CD90+ cardiac myofibroblast activation
por: Nural-Guvener, Hikmet F, et al.
Publicado: (2014)

Lineage Tracing of Cardiac Explant Derived Cells
por: Shenje, Lincoln T., et al.
Publicado: (2008)

Explanting Is an Ex Vivo Model of Renal Epithelial-Mesenchymal Transition
por: Winbanks, Catherine E., et al.
Publicado: (2011)

Relaxin inhibits cardiac fibrosis and endothelial–mesenchymal transition via the Notch pathway
por: Zhou, X, et al.
Publicado: (2015)

Numb prevents a complete epithelial–mesenchymal transition by modulating Notch signalling
por: Bocci, Federico, et al.
Publicado: (2017)

Relaxin inhibits cardiac fibrosis and endothelial–mesenchymal transition via the Notch pathway [Corrigendum]
Publicado: (2017)

The epicardium obscures interpretations on endothelial-to-mesenchymal transition in the mouse atrioventricular canal explant assay
por: Criem, Nathan, et al.
Publicado: (2018)

Interplay between BMP2 and Notch signaling in endothelial-mesenchymal transition: implications for cardiac fibrosis
por: Docshin, Pavel, et al.
Publicado: (2023)

Gene expression profile of epithelial cells and mesenchymal cells derived from limbal explant culture
por: Polisetti, Naresh, et al.
Publicado: (2010)

Endothelial and smooth muscle cells derived from human cardiac explants demonstrate angiogenic potential and suitable for design of cell-containing vascular grafts
por: Zakharova, I. S., et al.
Publicado: (2017)

Notch signaling: targeting cancer stem cells and epithelial-to-mesenchymal transition
por: Espinoza, Ingrid, et al.
Publicado: (2013)

Dose-dependency and reversibility of radiation-induced injury in cardiac explant-derived cells of mice
por: Luo, Lan, et al.
Publicado: (2017)

Interleukin-6 Mediates Post-Infarct Repair by Cardiac Explant-Derived Stem Cells
por: Mayfield, Audrey E, et al.
Publicado: (2017)

Isolation of human explant derived cardiac stem cells from cryopreserved heart tissue
por: Jackson, Robyn, et al.
Publicado: (2017)

The impact of patient co-morbidities on the regenerative capacity of cardiac explant-derived stem cells
por: Mayfield, Audrey E., et al.
Publicado: (2016)

Author Correction: The epicardium obscures interpretations on endothelial-to-mesenchymal transition in the mouse atrioventricular canal explant assay
por: Criem, Nathan, et al.
Publicado: (2020)

An Explant Assay for Assessing Cellular Behavior of the Cranial Mesenchyme
por: Sarkar, Anjali A., et al.
Publicado: (2013)

Cytoplasmic NOTCH and membrane-derived β-catenin link cell fate choice to epithelial-mesenchymal transition during myogenesis
por: Sieiro, Daniel, et al.
Publicado: (2016)

Notch signaling regulates vasculogenic mimicry and promotes cell morphogenesis and the epithelial-to-mesenchymal transition in pancreatic ductal adenocarcinoma
por: Benjakul, Nontawat, et al.
Publicado: (2022)

Nestin and Notch3 collaboratively regulate angiogenesis, collagen production, and endothelial–mesenchymal transition in lung endothelial cells
por: Daido, Wakako, et al.
Publicado: (2023)

Regulation of the epithelial to mesenchymal transition and metastasis by Raf kinase inhibitory protein-dependent Notch1 activity
por: Noh, Hae Sook, et al.
Publicado: (2015)

NUMB negatively regulates the epithelial-mesenchymal transition of triple-negative breast cancer by antagonizing Notch signaling
por: Zhang, Jianchao, et al.
Publicado: (2016)

Characterization of the Proteins Secreted by Equine Muscle-Derived Mesenchymal Stem Cells Exposed to Cartilage Explants in Osteoarthritis Model
por: Dechêne, Lola, et al.
Publicado: (2022)

Notch1 Affects Chemo-resistance Through Regulating Epithelial-Mesenchymal Transition (EMT) in Epithelial Ovarian cancer cells
por: Qian, Xue-qian, et al.
Publicado: (2020)

Radiation driven epithelial-mesenchymal transition is mediated by Notch signaling in breast cancer
por: Kim, Rae-Kwon, et al.
Publicado: (2016)

A “NOTCH” Deeper into the Epithelial-To-Mesenchymal Transition (EMT) Program in Breast Cancer
por: Kar, Rohan, et al.
Publicado: (2019)

Notch1 signaling regulates the epithelial–mesenchymal transition and invasion of breast cancer in a Slug-dependent manner
por: Shao, Shan, et al.
Publicado: (2015)

NOTCH2 negatively regulates metastasis and epithelial-Mesenchymal transition via TRAF6/AKT in nasopharyngeal carcinoma
por: Zou, You, et al.
Publicado: (2019)

Cigarette Smoke Impairs Airway Epithelial Wound Repair: Role of Modulation of Epithelial-Mesenchymal Transition Processes and Notch-1 Signaling
por: Di Vincenzo, Serena, et al.
Publicado: (2022)

Functional antagonism of chromatin modulators regulates epithelial-mesenchymal transition
por: Serresi, Michela, et al.
Publicado: (2021)

The NOTCH1-HEY1 pathway regulates self-renewal and epithelial-mesenchymal transition of salivary adenoid cystic carcinoma cells
por: Xie, Jing, et al.
Publicado: (2020)

Notch1 signaling induces epithelial-mesenchymal transition in lens epithelium cells during hypoxia
por: Liu, Lei, et al.
Publicado: (2017)

Inhibitor of DNA Binding 2 Inhibits Epithelial-Mesenchymal Transition via Up-Regulation of Notch3 in Breast Cancer
por: Wen, Xiao-Fen, et al.
Publicado: (2018)

Ethylene signals modulate the survival of Arabidopsis leaf explants
por: Shin, Seung Yong, et al.
Publicado: (2023)

Paraquat poisoning induced pulmonary epithelial mesenchymal transition through Notch1 pathway
por: Li, Tiegang, et al.
Publicado: (2017)

Notch3 Modulates Cardiac Fibroblast Proliferation, Apoptosis, and Fibroblast to Myofibroblast Transition via Negative Regulation of the RhoA/ROCK/Hif1α Axis
por: Shi, Jianli, et al.
Publicado: (2020)

Mesenchymal-endothelial transition-derived cells as a potential new regulatory target for cardiac hypertrophy
por: Dong, Wenyan, et al.
Publicado: (2020)

Up-regulation of S100A16 expression promotes epithelial-mesenchymal transition via Notch1 pathway in breast cancer
por: Zhou, Wenbin, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_njm7c938ofhv12s7f14lb9gujc