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EMT and Stem Cell-Like Properties Associated with HIF-2α Are Involved in Arsenite-Induced Transformation of Human Bronchial Epithelial Cells
BACKGROUND: Arsenic is well-established as a human carcinogen, but the molecular mechanisms leading to arsenic-induced carcinogenesis are complex and elusive. It is not been determined if the epithelial-mesenchymal transition (EMT) and stem cell-like properties contribute in causing to carcinogen-in...
Autores principales: | Xu, Yuan, Li, Yuan, Pang, Ying, Ling, Min, Shen, Lu, Yang, Xiaojun, Zhang, Jianping, Zhou, Jianwei, Wang, Xinru, Liu, Qizhan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3360629/ https://www.ncbi.nlm.nih.gov/pubmed/22662215 http://dx.doi.org/10.1371/journal.pone.0037765 |
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