Effect of Spermidine on Misfolding and Interactions of Alpha-Synuclein

Alpha-synuclein (α-Syn) is a 140 aa presynaptic protein which belongs to a group of natively unfolded proteins that are unstructured in aqueous solutions. The aggregation rate of α-Syn is accelerated in the presence of physiological levels of cellular polyamines. Here we applied single molecule AFM...

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Detalles Bibliográficos
Autores principales: Krasnoslobodtsev, Alexey V., Peng, Jie, Asiago, Josephat M., Hindupur, Jagadish, Rochet, Jean-Christophe, Lyubchenko, Yuri L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3360652/
https://www.ncbi.nlm.nih.gov/pubmed/22662273
http://dx.doi.org/10.1371/journal.pone.0038099

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3360652/
https://www.ncbi.nlm.nih.gov/pubmed/22662273
http://dx.doi.org/10.1371/journal.pone.0038099

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