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Regulation of Adipocyte 11β-Hydroxysteroid Dehydrogenase Type 1 (11β-HSD1) by CCAAT/Enhancer-Binding Protein (C/EBP) β Isoforms, LIP and LAP
11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) catalyses intracellular regeneration of active glucocorticoids, notably in liver and adipose tissue. 11β-HSD1 is increased selectively in adipose tissue in human obesity, a change implicated in the pathogenesis of metabolic syndrome. With high fat (...
Autores principales: | Esteves, Cristina L., Kelly, Val, Bégay, Valérie, Man, Tak Y., Morton, Nicholas M., Leutz, Achim, Seckl, Jonathan R., Chapman, Karen E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3360670/ https://www.ncbi.nlm.nih.gov/pubmed/22662254 http://dx.doi.org/10.1371/journal.pone.0037953 |
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