Autoantibody Epitope Spreading in the Pre-Clinical Phase Predicts Progression to Rheumatoid Arthritis

Rheumatoid arthritis (RA) is a prototypical autoimmune arthritis affecting nearly 1% of the world population and is a significant cause of worldwide disability. Though prior studies have demonstrated the appearance of RA-related autoantibodies years before the onset of clinical RA, the pattern of im...

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Detalles Bibliográficos
Autores principales: Sokolove, Jeremy, Bromberg, Reuven, Deane, Kevin D., Lahey, Lauren J., Derber, Lezlie A., Chandra, Piyanka E., Edison, Jess D., Gilliland, William R., Tibshirani, Robert J., Norris, Jill M., Holers, V. Michael, Robinson, William H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3360701/
https://www.ncbi.nlm.nih.gov/pubmed/22662108
http://dx.doi.org/10.1371/journal.pone.0035296

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