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Functional Analysis of a Breast Cancer-Associated Mutation in the Intracellular Domain of the Metalloprotease ADAM12

A recently identified breast cancer-associated mutation in the metalloprotease ADAM12 alters a potential dileucine trafficking signal, which could affect protein processing and cellular localization. ADAM12 belongs to the group of A Disintegrin And Metalloproteases (ADAMs), which are typically membr...

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Detalles Bibliográficos
Autores principales:	Stautz, Dorte, Wewer, Ulla M., Kveiborg, Marie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3360752/ https://www.ncbi.nlm.nih.gov/pubmed/22662180 http://dx.doi.org/10.1371/journal.pone.0037628

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