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Gender Differences in Associations of Glutamate Decarboxylase 1 Gene (GAD1) Variants with Panic Disorder

BACKGROUND: Panic disorder is common (5% prevalence) and females are twice as likely to be affected as males. The heritable component of panic disorder is estimated at 48%. Glutamic acid dehydrogenase GAD1, the key enzyme for the synthesis of the inhibitory and anxiolytic neurotransmitter GABA, is s...

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Detalles Bibliográficos
Autores principales:	Weber, Heike, Scholz, Claus Jürgen, Domschke, Katharina, Baumann, Christian, Klauke, Benedikt, Jacob, Christian P., Maier, Wolfgang, Fritze, Jürgen, Bandelow, Borwin, Zwanzger, Peter Michael, Lang, Thomas, Fehm, Lydia, Ströhle, Andreas, Hamm, Alfons, Gerlach, Alexander L., Alpers, Georg W., Kircher, Tilo, Wittchen, Hans-Ulrich, Arolt, Volker, Pauli, Paul, Deckert, Jürgen, Reif, Andreas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3360757/ https://www.ncbi.nlm.nih.gov/pubmed/22662185 http://dx.doi.org/10.1371/journal.pone.0037651

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