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Asymmetric positive feedback loops reliably control biological responses

Positive feedback is a common mechanism enabling biological systems to respond to stimuli in a switch-like manner. Such systems are often characterized by the requisite formation of a heterodimer where only one of the pair is subject to feedback. This ASymmetric Self-UpREgulation (ASSURE) motif is c...

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Detalles Bibliográficos
Autores principales: Ratushny, Alexander V, Saleem, Ramsey A, Sitko, Katherine, Ramsey, Stephen A, Aitchison, John D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Molecular Biology Organization 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3361002/
https://www.ncbi.nlm.nih.gov/pubmed/22531117
http://dx.doi.org/10.1038/msb.2012.10