Whole-exome Sequencing and an iPSC-Derived Cardiomyocyte Model Provides a Powerful Platform for Gene Discovery in Left Ventricular Hypertrophy

Rationale: Left ventricular hypertrophy (LVH) is a heritable predictor of cardiovascular disease, particularly in blacks. Objective: Determine the feasibility of combining evidence from two distinct but complementary experimental approaches to identify novel genetic predictors of increased LV mass....

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Detalles Bibliográficos
Autores principales: Zhi, D., Irvin, M. R., Gu, C. C., Stoddard, A. J., Lorier, R., Matter, A., Rao, D. C., Srinivasasainagendra, V., Tiwari, H. K., Turner, A., Broeckel, U., Arnett, D. K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2012
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3361011/
https://www.ncbi.nlm.nih.gov/pubmed/22654895
http://dx.doi.org/10.3389/fgene.2012.00092

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