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Glutathione Supplementation Attenuates Lipopolysaccharide-Induced Mitochondrial Dysfunction and Apoptosis in a Mouse Model of Acute Lung Injury
Acute lung injury (ALI) is a life threatening condition associated with hypoxemia, diffuse alveolar damage, inflammation, and loss of lung function. Lipopolysaccharide (LPS; endotoxin) from the outer membrane of Gram-negative bacteria is a major virulence factor involved in the development of ALI. T...
Autores principales: | Aggarwal, Saurabh, Dimitropoulou, Christiana, Lu, Qing, Black, Stephen M., Sharma, Shruti |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Research Foundation
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3361071/ https://www.ncbi.nlm.nih.gov/pubmed/22654772 http://dx.doi.org/10.3389/fphys.2012.00161 |
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