CD8(+) T Cells: GITR Matters

As many members of the tumor necrosis factor receptor superfamily, glucocorticoid-induced TNFR-related gene (GITR) plays multiple roles mostly in the cells of immune system. CD8(+) T cells are key players in the immunity against viruses and tumors, and GITR has been demonstrated to be an essential m...

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Detalles Bibliográficos
Autores principales: Ronchetti, Simona, Nocentini, Giuseppe, Petrillo, Maria Grazia, Riccardi, Carlo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Scientific World Journal 2012
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3361162/
https://www.ncbi.nlm.nih.gov/pubmed/22654588
http://dx.doi.org/10.1100/2012/308265
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author Ronchetti, Simona
Nocentini, Giuseppe
Petrillo, Maria Grazia
Riccardi, Carlo
author_facet Ronchetti, Simona
Nocentini, Giuseppe
Petrillo, Maria Grazia
Riccardi, Carlo
author_sort Ronchetti, Simona
collection PubMed
description As many members of the tumor necrosis factor receptor superfamily, glucocorticoid-induced TNFR-related gene (GITR) plays multiple roles mostly in the cells of immune system. CD8(+) T cells are key players in the immunity against viruses and tumors, and GITR has been demonstrated to be an essential molecule for these cells to mount an immune response. The aim of this paper is to focus on GITR function in CD8(+) cells, paying particular attention to numerous and recent studies that suggest its crucial role in mouse disease models.
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spelling pubmed-33611622012-05-31 CD8(+) T Cells: GITR Matters Ronchetti, Simona Nocentini, Giuseppe Petrillo, Maria Grazia Riccardi, Carlo ScientificWorldJournal Review Article As many members of the tumor necrosis factor receptor superfamily, glucocorticoid-induced TNFR-related gene (GITR) plays multiple roles mostly in the cells of immune system. CD8(+) T cells are key players in the immunity against viruses and tumors, and GITR has been demonstrated to be an essential molecule for these cells to mount an immune response. The aim of this paper is to focus on GITR function in CD8(+) cells, paying particular attention to numerous and recent studies that suggest its crucial role in mouse disease models. The Scientific World Journal 2012-04-30 /pmc/articles/PMC3361162/ /pubmed/22654588 http://dx.doi.org/10.1100/2012/308265 Text en Copyright © 2012 Simona Ronchetti et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Ronchetti, Simona
Nocentini, Giuseppe
Petrillo, Maria Grazia
Riccardi, Carlo
CD8(+) T Cells: GITR Matters
title CD8(+) T Cells: GITR Matters
title_full CD8(+) T Cells: GITR Matters
title_fullStr CD8(+) T Cells: GITR Matters
title_full_unstemmed CD8(+) T Cells: GITR Matters
title_short CD8(+) T Cells: GITR Matters
title_sort cd8(+) t cells: gitr matters
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3361162/
https://www.ncbi.nlm.nih.gov/pubmed/22654588
http://dx.doi.org/10.1100/2012/308265
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AT riccardicarlo cd8tcellsgitrmatters

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