Classification of Inhibitors of Hepatic Organic Anion Transporting Polypeptides (OATPs): Influence of Protein Expression on Drug–Drug Interactions

[Image: see text] The hepatic organic anion transporting polypeptides (OATPs) influence the pharmacokinetics of several drug classes and are involved in many clinical drug–drug interactions. Predicting potential interactions with OATPs is, therefore, of value. Here, we developed in vitro and in sili...

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Detalles Bibliográficos
Autores principales: Karlgren, Maria, Vildhede, Anna, Norinder, Ulf, Wisniewski, Jacek R., Kimoto, Emi, Lai, Yurong, Haglund, Ulf, Artursson, Per
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2012
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3361267/
https://www.ncbi.nlm.nih.gov/pubmed/22541068
http://dx.doi.org/10.1021/jm300212s

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3361267/
https://www.ncbi.nlm.nih.gov/pubmed/22541068
http://dx.doi.org/10.1021/jm300212s

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