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In Silico profiling of deleterious amino acid substitutions of potential pathological importance in haemophlia A and haemophlia B
BACKGROUND: In this study, instead of current biochemical methods, the effects of deleterious amino acid substitutions in F8 and F9 gene upon protein structure and function were assayed by means of computational methods and information from the databases. Deleterious substitutions of F8 and F9 are r...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3361463/ https://www.ncbi.nlm.nih.gov/pubmed/22423892 http://dx.doi.org/10.1186/1423-0127-19-30 |