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BMP2 and mechanical loading cooperatively regulate immediate early signalling events in the BMP pathway

BACKGROUND: Efficient osteogenic differentiation is highly dependent on coordinated signals arising from growth factor signalling and mechanical forces. Bone morphogenetic proteins (BMPs) are secreted proteins that trigger Smad and non-Smad pathways and thereby influence transcriptional and non-tran...

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Detalles Bibliográficos
Autores principales: Kopf, Jessica, Petersen, Ansgar, Duda, Georg N, Knaus, Petra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3361481/
https://www.ncbi.nlm.nih.gov/pubmed/22540193
http://dx.doi.org/10.1186/1741-7007-10-37