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The outcome and predictive factors of sunitinib therapy in advanced gastrointestinal stromal tumors (GIST) after imatinib failure - one institution study

BACKGROUND: Gastrointestinal stromal tumors (GIST) mutational status is recognized factor related to the results of tyrosine kinase inhibitors therapy such as imatinib (IM) or sunitinib (SU). Arterial hypertension (AH) is common adverse event related to SU, reported as predictive factor in renal cel...

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Detalles Bibliográficos
Autores principales: Rutkowski, Piotr, Bylina, Elżbieta, Klimczak, Anna, Świtaj, Tomasz, Falkowski, Sławomir, Kroc, Jacek, Ługowska, Iwona, Brzeskwiniewicz, Magdalena, Melerowicz, Wojciech, Osuch, Czesław, Mierzejewska, Ewa, Wasielewski, Kacper, Woźniak, Agnieszka, Grzesiakowska, Urszula, Nowecki, Zbigniew I, Siedlecki, Janusz A, Limon, Janusz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3361487/
https://www.ncbi.nlm.nih.gov/pubmed/22439647
http://dx.doi.org/10.1186/1471-2407-12-107