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The First European Interdisciplinary Ewing Sarcoma Research Summit
The European Network for Cancer Research in Children and Adolescents (ENCCA) provides an interaction platform for stakeholders in research and care of children with cancer. Among ENCCA objectives is the establishment of biology-based prioritization mechanisms for the selection of innovative targets,...
| Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Research Foundation
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3361960/ https://www.ncbi.nlm.nih.gov/pubmed/22662320 http://dx.doi.org/10.3389/fonc.2012.00054 |
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| author | Kovar, Heinrich Alonso, Javier Aman, Pierre Aryee, Dave N. T. Ban, Jozef Burchill, Sue A. Burdach, Stefan De Alava, Enrique Delattre, Olivier Dirksen, Uta Fourtouna, Argyro Fulda, Simone Helman, Lee J. Herrero-Martin, David Hogendoorn, Pancras C. W. Kontny, Udo Lawlor, Elizabeth R. Lessnick, Stephen L. Llombart-Bosch, Antonio Metzler, Markus Moriggl, Richard Niedan, Stephan Potratz, Jenny Redini, Françoise Richter, Günther H. S. Riedmann, Lucia T. Rossig, Claudia Schäfer, Beat W. Schwentner, Raphaela Scotlandi, Katia Sorensen, Poul H. Staege, Martin S. Tirode, Franck Toretsky, Jeffrey Ventura, Selena Eggert, Angelika Ladenstein, Ruth |
| author_facet | Kovar, Heinrich Alonso, Javier Aman, Pierre Aryee, Dave N. T. Ban, Jozef Burchill, Sue A. Burdach, Stefan De Alava, Enrique Delattre, Olivier Dirksen, Uta Fourtouna, Argyro Fulda, Simone Helman, Lee J. Herrero-Martin, David Hogendoorn, Pancras C. W. Kontny, Udo Lawlor, Elizabeth R. Lessnick, Stephen L. Llombart-Bosch, Antonio Metzler, Markus Moriggl, Richard Niedan, Stephan Potratz, Jenny Redini, Françoise Richter, Günther H. S. Riedmann, Lucia T. Rossig, Claudia Schäfer, Beat W. Schwentner, Raphaela Scotlandi, Katia Sorensen, Poul H. Staege, Martin S. Tirode, Franck Toretsky, Jeffrey Ventura, Selena Eggert, Angelika Ladenstein, Ruth |
| author_sort | Kovar, Heinrich |
| collection | PubMed |
| description | The European Network for Cancer Research in Children and Adolescents (ENCCA) provides an interaction platform for stakeholders in research and care of children with cancer. Among ENCCA objectives is the establishment of biology-based prioritization mechanisms for the selection of innovative targets, drugs, and prognostic markers for validation in clinical trials. Specifically for sarcomas, there is a burning need for novel treatment options, since current chemotherapeutic treatment protocols have met their limits. This is most obvious for metastatic Ewing sarcoma (ES), where long term survival rates are still below 20%. Despite significant progress in our understanding of ES biology, clinical translation of promising laboratory results has not yet taken place due to fragmentation of research and lack of an institutionalized discussion forum. To fill this gap, ENCCA assembled 30 European expert scientists and five North American opinion leaders in December 2011 to exchange thoughts and discuss the state of the art in ES research and latest results from the bench, and to propose biological studies and novel promising therapeutics for the upcoming European EWING2008 and EWING2012 clinical trials. |
| format | Online Article Text |
| id | pubmed-3361960 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2012 |
| publisher | Frontiers Research Foundation |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-33619602012-06-01 The First European Interdisciplinary Ewing Sarcoma Research Summit Kovar, Heinrich Alonso, Javier Aman, Pierre Aryee, Dave N. T. Ban, Jozef Burchill, Sue A. Burdach, Stefan De Alava, Enrique Delattre, Olivier Dirksen, Uta Fourtouna, Argyro Fulda, Simone Helman, Lee J. Herrero-Martin, David Hogendoorn, Pancras C. W. Kontny, Udo Lawlor, Elizabeth R. Lessnick, Stephen L. Llombart-Bosch, Antonio Metzler, Markus Moriggl, Richard Niedan, Stephan Potratz, Jenny Redini, Françoise Richter, Günther H. S. Riedmann, Lucia T. Rossig, Claudia Schäfer, Beat W. Schwentner, Raphaela Scotlandi, Katia Sorensen, Poul H. Staege, Martin S. Tirode, Franck Toretsky, Jeffrey Ventura, Selena Eggert, Angelika Ladenstein, Ruth Front Oncol Oncology The European Network for Cancer Research in Children and Adolescents (ENCCA) provides an interaction platform for stakeholders in research and care of children with cancer. Among ENCCA objectives is the establishment of biology-based prioritization mechanisms for the selection of innovative targets, drugs, and prognostic markers for validation in clinical trials. Specifically for sarcomas, there is a burning need for novel treatment options, since current chemotherapeutic treatment protocols have met their limits. This is most obvious for metastatic Ewing sarcoma (ES), where long term survival rates are still below 20%. Despite significant progress in our understanding of ES biology, clinical translation of promising laboratory results has not yet taken place due to fragmentation of research and lack of an institutionalized discussion forum. To fill this gap, ENCCA assembled 30 European expert scientists and five North American opinion leaders in December 2011 to exchange thoughts and discuss the state of the art in ES research and latest results from the bench, and to propose biological studies and novel promising therapeutics for the upcoming European EWING2008 and EWING2012 clinical trials. Frontiers Research Foundation 2012-05-29 /pmc/articles/PMC3361960/ /pubmed/22662320 http://dx.doi.org/10.3389/fonc.2012.00054 Text en Copyright © 2012 Kovar, Alonso, Aman, Aryee, Ban, Burchill, Burdach, De Alava, Delattre, Dirksen, Fourtouna, Fulda, Helman, Herrero-Martin, Hogendoorn, Kontny, Lawlor, Lessnick, Llombart-Bosch, Metzler, Moriggl, Niedan, Potratz, Redini, Richter, Riedmann, Rossig, Schäfer, Schwentner, Scotlandi, Sorensen, Staege, Tirode, Toretsky, Ventura, Eggert and Ladenstein. http://www.frontiersin.org/licenseagreement This is an open-access article distributed under the terms of the Creative Commons Attribution Non Commercial License, which permits non-commercial use, distribution, and reproduction in other forums, provided the original authors and source are credited. |
| spellingShingle | Oncology Kovar, Heinrich Alonso, Javier Aman, Pierre Aryee, Dave N. T. Ban, Jozef Burchill, Sue A. Burdach, Stefan De Alava, Enrique Delattre, Olivier Dirksen, Uta Fourtouna, Argyro Fulda, Simone Helman, Lee J. Herrero-Martin, David Hogendoorn, Pancras C. W. Kontny, Udo Lawlor, Elizabeth R. Lessnick, Stephen L. Llombart-Bosch, Antonio Metzler, Markus Moriggl, Richard Niedan, Stephan Potratz, Jenny Redini, Françoise Richter, Günther H. S. Riedmann, Lucia T. Rossig, Claudia Schäfer, Beat W. Schwentner, Raphaela Scotlandi, Katia Sorensen, Poul H. Staege, Martin S. Tirode, Franck Toretsky, Jeffrey Ventura, Selena Eggert, Angelika Ladenstein, Ruth The First European Interdisciplinary Ewing Sarcoma Research Summit |
| title | The First European Interdisciplinary Ewing Sarcoma Research Summit |
| title_full | The First European Interdisciplinary Ewing Sarcoma Research Summit |
| title_fullStr | The First European Interdisciplinary Ewing Sarcoma Research Summit |
| title_full_unstemmed | The First European Interdisciplinary Ewing Sarcoma Research Summit |
| title_short | The First European Interdisciplinary Ewing Sarcoma Research Summit |
| title_sort | first european interdisciplinary ewing sarcoma research summit |
| topic | Oncology |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3361960/ https://www.ncbi.nlm.nih.gov/pubmed/22662320 http://dx.doi.org/10.3389/fonc.2012.00054 |
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