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Insulin Receptor Expression and Activity in the Brains of Nondiabetic Sporadic Alzheimer's Disease Cases
We investigated the contents of the insulin receptor-beta subunit (IRβ) and [Tyr1162/1163]-phosphorylated IRβ as surrogate indices of total IR content and IR activation in postmortem hippocampal formation brain specimens from nondiabetic sporadic Alzheimer's disease (AD) cases. We found no sign...
Autores principales: | Ho, Lap, Yemul, Shrishailam, Knable, Lindsay, Katsel, Pavel, Zhao, Rudy, Haroutunian, Vahram, Pasinetti, Giulio Maria |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3362009/ https://www.ncbi.nlm.nih.gov/pubmed/22666619 http://dx.doi.org/10.1155/2012/321280 |
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