Modified Carbon Nanotube Paste Electrode for Voltammetric Determination of Carbidopa, Folic Acid, and Tryptophan

A simple and convenient method is described for voltammetric determination of carbidopa (CD), based on its electrochemical oxidation at a modified multiwall carbon nanotube paste electrode. Under optimized conditions, the proposed method exhibited acceptable analytical performances in terms of linea...

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Autores principales: Esfandiari Baghbamidi, Sakineh, Beitollahi, Hadi, Karimi-Maleh, Hassan, Soltani-Nejad, Somayeh, Soltani-Nejad, Vahhab, Roodsaz, Sara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3362041/
https://www.ncbi.nlm.nih.gov/pubmed/22666634
http://dx.doi.org/10.1155/2012/305872
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author Esfandiari Baghbamidi, Sakineh
Beitollahi, Hadi
Karimi-Maleh, Hassan
Soltani-Nejad, Somayeh
Soltani-Nejad, Vahhab
Roodsaz, Sara
author_facet Esfandiari Baghbamidi, Sakineh
Beitollahi, Hadi
Karimi-Maleh, Hassan
Soltani-Nejad, Somayeh
Soltani-Nejad, Vahhab
Roodsaz, Sara
author_sort Esfandiari Baghbamidi, Sakineh
collection PubMed
description A simple and convenient method is described for voltammetric determination of carbidopa (CD), based on its electrochemical oxidation at a modified multiwall carbon nanotube paste electrode. Under optimized conditions, the proposed method exhibited acceptable analytical performances in terms of linearity (over the concentration range from 0.1 to 700.0 μM), detection limit (65.0 nM), and reproducibility (RSD = 2.5%) for a solution containing CD. Also, square wave voltammetry (SWV) was used for simultaneous determination of CD, folic acid (FA), and tryptophan (TRP) at the modified electrode. To further validate its possible application, the method was used for the quantification of CD, FA, and TRP in urine samples.
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spelling pubmed-33620412012-06-04 Modified Carbon Nanotube Paste Electrode for Voltammetric Determination of Carbidopa, Folic Acid, and Tryptophan Esfandiari Baghbamidi, Sakineh Beitollahi, Hadi Karimi-Maleh, Hassan Soltani-Nejad, Somayeh Soltani-Nejad, Vahhab Roodsaz, Sara J Anal Methods Chem Research Article A simple and convenient method is described for voltammetric determination of carbidopa (CD), based on its electrochemical oxidation at a modified multiwall carbon nanotube paste electrode. Under optimized conditions, the proposed method exhibited acceptable analytical performances in terms of linearity (over the concentration range from 0.1 to 700.0 μM), detection limit (65.0 nM), and reproducibility (RSD = 2.5%) for a solution containing CD. Also, square wave voltammetry (SWV) was used for simultaneous determination of CD, folic acid (FA), and tryptophan (TRP) at the modified electrode. To further validate its possible application, the method was used for the quantification of CD, FA, and TRP in urine samples. Hindawi Publishing Corporation 2012 2012-05-15 /pmc/articles/PMC3362041/ /pubmed/22666634 http://dx.doi.org/10.1155/2012/305872 Text en Copyright © 2012 Sakineh Esfandiari Baghbamidi et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Esfandiari Baghbamidi, Sakineh
Beitollahi, Hadi
Karimi-Maleh, Hassan
Soltani-Nejad, Somayeh
Soltani-Nejad, Vahhab
Roodsaz, Sara
Modified Carbon Nanotube Paste Electrode for Voltammetric Determination of Carbidopa, Folic Acid, and Tryptophan
title Modified Carbon Nanotube Paste Electrode for Voltammetric Determination of Carbidopa, Folic Acid, and Tryptophan
title_full Modified Carbon Nanotube Paste Electrode for Voltammetric Determination of Carbidopa, Folic Acid, and Tryptophan
title_fullStr Modified Carbon Nanotube Paste Electrode for Voltammetric Determination of Carbidopa, Folic Acid, and Tryptophan
title_full_unstemmed Modified Carbon Nanotube Paste Electrode for Voltammetric Determination of Carbidopa, Folic Acid, and Tryptophan
title_short Modified Carbon Nanotube Paste Electrode for Voltammetric Determination of Carbidopa, Folic Acid, and Tryptophan
title_sort modified carbon nanotube paste electrode for voltammetric determination of carbidopa, folic acid, and tryptophan
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3362041/
https://www.ncbi.nlm.nih.gov/pubmed/22666634
http://dx.doi.org/10.1155/2012/305872
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