A Case of Paraneoplastic Demyelinating Motor Polyneuropathy

Peripheral neuropathy is commonly accompanied by cancer but demyelinating ones are not commonly reported. We report the clinical, neurophysiological, and biological characteristics of an 82-year-old patient who presented with a demyelinating motor neuropathy and high titre of anti-ganglioside antibo...

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Autores principales: Mostoufizadeh, Sohrab, Souri, Maryam, de Seze, Jérôme
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2012
Materias:
Published online: April, 2012
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3362224/
https://www.ncbi.nlm.nih.gov/pubmed/22649345
http://dx.doi.org/10.1159/000338296
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author Mostoufizadeh, Sohrab
Souri, Maryam
de Seze, Jérôme
author_facet Mostoufizadeh, Sohrab
Souri, Maryam
de Seze, Jérôme
author_sort Mostoufizadeh, Sohrab
collection PubMed
description Peripheral neuropathy is commonly accompanied by cancer but demyelinating ones are not commonly reported. We report the clinical, neurophysiological, and biological characteristics of an 82-year-old patient who presented with a demyelinating motor neuropathy and high titre of anti-ganglioside antibodies associated with oesophageal cancer. The neurological course worsened rapidly despite immunotherapy, leading to a bedridden status. We propose to suspect a paraneoplastic origin in older patients or when the clinical course progresses rapidly within a few weeks or months.
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spelling pubmed-33622242012-05-30 A Case of Paraneoplastic Demyelinating Motor Polyneuropathy Mostoufizadeh, Sohrab Souri, Maryam de Seze, Jérôme Case Rep Neurol Published online: April, 2012 Peripheral neuropathy is commonly accompanied by cancer but demyelinating ones are not commonly reported. We report the clinical, neurophysiological, and biological characteristics of an 82-year-old patient who presented with a demyelinating motor neuropathy and high titre of anti-ganglioside antibodies associated with oesophageal cancer. The neurological course worsened rapidly despite immunotherapy, leading to a bedridden status. We propose to suspect a paraneoplastic origin in older patients or when the clinical course progresses rapidly within a few weeks or months. S. Karger AG 2012-04-25 /pmc/articles/PMC3362224/ /pubmed/22649345 http://dx.doi.org/10.1159/000338296 Text en Copyright © 2012 by S. Karger AG, Basel http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-Noncommercial-No-Derivative-Works License (http://creativecommons.org/licenses/by-nc-nd/3.0/). Users may download, print and share this work on the Internet for noncommercial purposes only, provided the original work is properly cited, and a link to the original work on http://www.karger.com and the terms of this license are included in any shared versions.
spellingShingle Published online: April, 2012
Mostoufizadeh, Sohrab
Souri, Maryam
de Seze, Jérôme
A Case of Paraneoplastic Demyelinating Motor Polyneuropathy
title A Case of Paraneoplastic Demyelinating Motor Polyneuropathy
title_full A Case of Paraneoplastic Demyelinating Motor Polyneuropathy
title_fullStr A Case of Paraneoplastic Demyelinating Motor Polyneuropathy
title_full_unstemmed A Case of Paraneoplastic Demyelinating Motor Polyneuropathy
title_short A Case of Paraneoplastic Demyelinating Motor Polyneuropathy
title_sort case of paraneoplastic demyelinating motor polyneuropathy
topic Published online: April, 2012
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3362224/
https://www.ncbi.nlm.nih.gov/pubmed/22649345
http://dx.doi.org/10.1159/000338296
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