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Convergent Evolution of Calcineurin Pathway Roles in Thermotolerance and Virulence in Candida glabrata
Candida glabrata is an emerging human fungal pathogen that is frequently drug tolerant, resulting in difficulties in treatment and a higher mortality in immunocompromised patients. The calcium-activated protein phosphatase calcineurin plays critical roles in controlling drug tolerance, hyphal growth...
Autores principales: | Chen, Ying-Lien, Konieczka, Jay H., Springer, Deborah J., Bowen, Samantha E., Zhang, Jing, Silao, Fitz Gerald S., Bungay, Alice Alma C., Bigol, Ursela G., Nicolas, Marilou G., Abraham, Soman N., Thompson, Dawn A., Regev, Aviv, Heitman, Joseph |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Genetics Society of America
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3362297/ https://www.ncbi.nlm.nih.gov/pubmed/22690377 http://dx.doi.org/10.1534/g3.112.002279 |
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