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Local anesthetic inhibition of a bacterial sodium channel
Recent structural breakthroughs with the voltage-gated sodium channel from Arcobacter butzleri suggest that such bacterial channels may provide a structural platform to advance the understanding of eukaryotic sodium channel gating and pharmacology. We therefore set out to determine whether compounds...
Autores principales: | Lee, Sora, Goodchild, Samuel J., Ahern, Christopher A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3362524/ https://www.ncbi.nlm.nih.gov/pubmed/22641643 http://dx.doi.org/10.1085/jgp.201210779 |
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