Lack of Correlation between Outcomes of Membrane Repair Assay and Correction of Dystrophic Changes in Experimental Therapeutic Strategy in Dysferlinopathy

Mutations in the dysferlin gene are the cause of Limb-girdle Muscular Dystrophy type 2B and Miyoshi Myopathy. The dysferlin protein has been implicated in sarcolemmal resealing, leading to the idea that the pathophysiology of dysferlin deficiencies is due to a deficit in membrane repair. Here, we sh...

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Detalles Bibliográficos
Autores principales: Lostal, William, Bartoli, Marc, Roudaut, Carinne, Bourg, Nathalie, Krahn, Martin, Pryadkina, Marina, Borel, Perrine, Suel, Laurence, Roche, Joseph A., Stockholm, Daniel, Bloch, Robert J., Levy, Nicolas, Bashir, Rumaisa, Richard, Isabelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3362551/
https://www.ncbi.nlm.nih.gov/pubmed/22666441
http://dx.doi.org/10.1371/journal.pone.0038036

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3362551/
https://www.ncbi.nlm.nih.gov/pubmed/22666441
http://dx.doi.org/10.1371/journal.pone.0038036

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