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Citrulline a More Suitable Substrate than Arginine to Restore NO Production and the Microcirculation during Endotoxemia
BACKGROUND: Impaired microcirculation during endotoxemia correlates with a disturbed arginine-nitric oxide (NO) metabolism and is associated with deteriorating organ function. Improving the organ perfusion in endotoxemia, as often seen in patients with severe infection or systemic inflammatory respo...
Autores principales: | Wijnands, Karolina A. P., Vink, Hans, Briedé, Jacob J., van Faassen, Ernst E., Lamers, Wouter H., Buurman, Wim A., Poeze, Martijn |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3362574/ https://www.ncbi.nlm.nih.gov/pubmed/22666356 http://dx.doi.org/10.1371/journal.pone.0037439 |
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