Autoimmunity in CD73/Ecto-5′-Nucleotidase Deficient Mice Induces Renal Injury

Extracellular adenosine formed by 5′-ectonucleotidase (CD73) is involved in tubulo-glomerular feedback in the kidney but is also known to be an important immune modulator. Since CD73(−/−)mutant mice exhibit a vascular proinflammatory phenotype, we asked whether long term lack of CD73 causes inflamma...

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Detalles Bibliográficos
Autores principales: Blume, Cornelia, Felix, Agnieszka, Shushakova, Nelli, Gueler, Faikah, Falk, Christine Susanne, Haller, Hermann, Schrader, Juergen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3362584/
https://www.ncbi.nlm.nih.gov/pubmed/22666342
http://dx.doi.org/10.1371/journal.pone.0037100

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3362584/
https://www.ncbi.nlm.nih.gov/pubmed/22666342
http://dx.doi.org/10.1371/journal.pone.0037100

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