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ZyFISH: A Simple, Rapid and Reliable Zygosity Assay for Transgenic Mice
Microinjection of DNA constructs into fertilized mouse oocytes typically results in random transgene integration at a single genomic locus. The resulting transgenic founders can be used to establish hemizygous transgenic mouse lines. However, practical and experimental reasons often require that suc...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3362593/ https://www.ncbi.nlm.nih.gov/pubmed/22666404 http://dx.doi.org/10.1371/journal.pone.0037881 |