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Experimental Induction of Paromomycin Resistance in Antimony-Resistant Strains of L. donovani: Outcome Dependent on In Vitro Selection Protocol

Paromomycin (PMM) has recently been introduced for treatment of visceral leishmaniasis in India. Although no clinical resistance has yet been reported, proactive vigilance should be warranted. The present in vitro study compared the outcome and stability of experimental PMM-resistance induction on p...

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Detalles Bibliográficos
Autores principales: Hendrickx, Sarah, Inocêncio da Luz, Raquel Andrea, Bhandari, Vasundhra, Kuypers, Kristel, Shaw, Craig D., Lonchamp, Julien, Salotra, Poonam, Carter, Katharine, Sundar, Shyam, Rijal, Suman, Dujardin, Jean-Claude, Cos, Paul, Maes, Louis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3362622/
https://www.ncbi.nlm.nih.gov/pubmed/22666513
http://dx.doi.org/10.1371/journal.pntd.0001664