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Quantitative genome re-sequencing defines multiple mutations conferring chloroquine resistance in rodent malaria
BACKGROUND: Drug resistance in the malaria parasite Plasmodium falciparum severely compromises the treatment and control of malaria. A knowledge of the critical mutations conferring resistance to particular drugs is important in understanding modes of drug action and mechanisms of resistances. They...
Autores principales: | Kinga Modrzynska, Katarzyna, Creasey, Alison, Loewe, Laurence, Cezard, Timothee, Trindade Borges, Sofia, Martinelli, Axel, Rodrigues, Louise, Cravo, Pedro, Blaxter, Mark, Carter, Richard, Hunt, Paul |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3362770/ https://www.ncbi.nlm.nih.gov/pubmed/22435897 http://dx.doi.org/10.1186/1471-2164-13-106 |
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