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The Yeast Ubr1 Ubiquitin Ligase Participates in a Prominent Pathway That Targets Cytosolic Thermosensitive Mutants for Degradation

Mutations causing protein misfolding and proteolysis are associated with many genetic diseases. The degradation of these aberrant proteins typically is mediated by protein-quality control pathways that recognize misfolded domains. Several E3 ubiquitin ligases have been shown to target cytosolic misf...

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Detalles Bibliográficos
Autores principales:	Khosrow-Khavar, Farzin, Fang, Nancy N., Ng, Alex H. M., Winget, Jason M., Comyn, Sophie A., Mayor, Thibault
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Genetics Society of America 2012
Materias:	Investigations
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3362944/ https://www.ncbi.nlm.nih.gov/pubmed/22670231 http://dx.doi.org/10.1534/g3.111.001933

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