Cargando…

Cholesteryl ester transfer-protein modulator and inhibitors and their potential for the treatment of cardiovascular diseases

Elevated low-density lipoprotein (LDL) cholesterol and lowered high-density lipoprotein (HDL) cholesterol are important risk factors for cardiovascular disease. Accordingly, raising HDL cholesterol induced by cholesteryl ester transfer protein (CETP) inhibition is an attractive approach for reducing...

Descripción completa

Detalles Bibliográficos
Autor principal:	Shinkai, Hisashi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2012
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3363149/ https://www.ncbi.nlm.nih.gov/pubmed/22661899 http://dx.doi.org/10.2147/VHRM.S25238

Ejemplares similares

Cholesteryl ester transfer protein: at the heart of the action of lipid-modulating therapy with statins, fibrates, niacin, and cholesteryl ester transfer protein inhibitors
por: Chapman, M. John, et al.
Publicado: (2010)

Cholesteryl ester transfer protein inhibitors for dyslipidemia: focus on dalcetrapib
por: Goldberg, Alyse S, et al.
Publicado: (2012)

Assessing the mechanisms of cholesteryl ester transfer protein inhibitors
por: Zhang, Meng, et al.
Publicado: (2017)

Cholesteryl Ester Transfer Protein (CETP) Deficiency and CETP Inhibitors
por: Mabuchi, Hiroshi, et al.
Publicado: (2014)

Quinoline-3-carboxamide Derivatives as Potential Cholesteryl Ester Transfer Protein Inhibitors
por: Li, Wen-Yan, et al.
Publicado: (2012)

Cholesteryl ester transfer protein (CETP) as a drug target for cardiovascular disease
por: Schmidt, Amand F., et al.
Publicado: (2021)

Comparative studies of three cholesteryl ester transfer proteins and their interactions with known inhibitors
por: Wang, Ziyun, et al.
Publicado: (2017)

Cholesteryl Ester Transfer Protein Inhibitors in the Treatment of Dyslipidemia: A Systematic Review and Meta-Analysis
por: Li, Chuanwei, et al.
Publicado: (2013)

Patient considerations and clinical impact of cholesteryl ester transfer protein inhibitors in the management of dyslipidemia: focus on anacetrapib
por: Miyares, Marta A, et al.
Publicado: (2012)

Cholesteryl Ester Transfer Protein Gene Polymorphisms and Longevity Syndrome
por: Kolovou, Genovefa, et al.
Publicado: (2010)

Structure-based mechanism and inhibition of cholesteryl ester transfer protein
por: Xue, Han, et al.
Publicado: (2023)

Cholesteryl Ester Transfer Protein Inhibition Reduces Major Adverse Cardiovascular Events by Lowering Apolipoprotein B Levels
por: Nelson, Adam J., et al.
Publicado: (2022)

Cholesteryl Ester Transfer Protein Inhibition for Preventing Cardiovascular Events: JACC Review Topic of the Week
por: Armitage, Jane, et al.
Publicado: (2019)

How cholesteryl ester transfer protein can also be a potential triglyceride transporter
por: Chirasani, Venkat R., et al.
Publicado: (2017)

Cholesteryl Ester Transfer Protein Gene and Effectiveness of Lipid Lowering of Atorvastatin
por: Kolovou, Genovefa, et al.
Publicado: (2010)

Cholesteryl ester transfer protein: ace of spades, queen of hearts, or the joker?
por: Miller, Norman E.
Publicado: (2015)

REVEAL Study: Reveals the Limitations of Cholesteryl Ester Transfer Protein Inhibition
por: Pareek, Anil, et al.
Publicado: (2018)

The cholesteryl ester transfer protein (CETP) raises cholesterol levels in the brain
por: Oestereich, Felix, et al.
Publicado: (2022)

Design, Synthesis, and Biological Evaluation of Benzylamino-Methanone Based Cholesteryl Ester Transfer Protein Inhibitors
por: Sheikha, Ghassan Abu, et al.
Publicado: (2010)

Roles of peripheral lipoproteins and cholesteryl ester transfer protein in the vascular contributions to cognitive impairment and dementia
por: Poliakova, Tetiana, et al.
Publicado: (2023)

Leoligin, the major lignan from Edelweiss, activates cholesteryl ester transfer protein
por: Duwensee, Kristina, et al.
Publicado: (2011)

The effect of cholesteryl ester transfer protein on pancreatic beta cell dysfunction in mice
por: Guo, Wen, et al.
Publicado: (2016)

Serum amyloid A augments the atherogenic effects of cholesteryl ester transfer protein
por: Ji, Ailing, et al.
Publicado: (2023)

Cholesteryl ester transfer protein inhibitors: from high-density lipoprotein cholesterol to low-density lipoprotein cholesterol lowering agents?
por: Nurmohamed, Nick S, et al.
Publicado: (2021)

Cholesterol is Inefficiently Converted to Cholesteryl Esters in the Blood of Cardiovascular Disease Patients
por: Gerl, Mathias J., et al.
Publicado: (2018)

CoMFA, CoMSIA and Eigenvalue Analysis on Dibenzodioxepinone and Dibenzodioxocinone Derivatives as Cholesteryl Ester Transfer Protein Inhibitors
por: Xiong, Xu-qiong, et al.
Publicado: (2008)

Design, Synthesis and Biological Evaluation of N,N-Substituted Amine Derivatives as Cholesteryl Ester Transfer Protein Inhibitors
por: Wang, Xinran, et al.
Publicado: (2017)

Lipoprotein signatures of cholesteryl ester transfer protein and HMG-CoA reductase inhibition
por: Kettunen, Johannes, et al.
Publicado: (2019)

Serum Cholesteryl Ester Transfer Protein (CETP) and Sortilin (SORT) in Patients with Psoriasis with Relation to Systemic Treatment
por: Nowowiejska, Julia, et al.
Publicado: (2022)

Elevated cholesteryl ester transfer and phospholipid transfer proteins aggravated psoriasis in imiquimod-induced mouse models
por: Chen, Jun, et al.
Publicado: (2022)

The role of common variants of the cholesteryl ester transfer protein gene in left main coronary artery disease
por: Kolovou, Genovefa, et al.
Publicado: (2011)

Quantitative Prediction of Human Pharmacokinetics and Pharmacodynamics of CKD519, a Potent Inhibitor of Cholesteryl Ester Transfer Protein (CETP)
por: Choi, Suein, et al.
Publicado: (2019)

Lipid Exchange Mechanism of the Cholesteryl Ester Transfer Protein Clarified by Atomistic and Coarse-grained Simulations
por: Koivuniemi, Artturi, et al.
Publicado: (2012)

How Anacetrapib Inhibits the Activity of the Cholesteryl Ester Transfer Protein? Perspective through Atomistic Simulations
por: Äijänen, Tarja, et al.
Publicado: (2014)

Meta-analysis of Cholesteryl Ester Transfer Protein TaqIB Polymorphism and Risk of Myocardial Infarction
por: Cao, Min, et al.
Publicado: (2014)

Correction: Lipoprotein signatures of cholesteryl ester transfer protein and HMG-CoA reductase inhibition
por: Kettunen, Johannes, et al.
Publicado: (2020)

Cholesteryl Ester Transfer Protein Impairs Triglyceride Clearance via Androgen Receptor in Male Mice
por: Palmisano, Brian T., et al.
Publicado: (2020)

Cholesteryl Ester Transfer Protein (CETP) Polymorphisms Affect mRNA Splicing, HDL Levels, and Sex-Dependent Cardiovascular Risk
por: Papp, Audrey C., et al.
Publicado: (2012)

Human cholesteryl ester transfer protein lacks lipopolysaccharide transfer activity, but worsens inflammation and sepsis outcomes in mice
por: Dusuel, Aloïs, et al.
Publicado: (2020)

Genetic variations of cholesteryl ester transfer protein and diet interactions in relation to lipid profiles and coronary heart disease: a systematic review
por: Mirmiran, Parvin, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_drmjr0s4eav91d39jpf95um3fu