XV(th )QTLMAS: simulated dataset

BACKGROUND: Our aim was to simulate the data for the QTLMAS2011 workshop following a pig-type family structure under an oligogenic model, each QTL being specific. RESULTS: The population comprised 3000 individuals issued from 20 sires and 200 dams. Within each family, 10 progenies belonged to the ex...

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Detalles Bibliográficos
Autores principales: Elsen, Jean-Michel, Tesseydre, Simon, Filangi, Olivier, Le Roy, Pascale, Demeure, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Proceedings
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3363151/
https://www.ncbi.nlm.nih.gov/pubmed/22640408
http://dx.doi.org/10.1186/1753-6561-6-S2-S1
Descripción
Sumario:BACKGROUND: Our aim was to simulate the data for the QTLMAS2011 workshop following a pig-type family structure under an oligogenic model, each QTL being specific. RESULTS: The population comprised 3000 individuals issued from 20 sires and 200 dams. Within each family, 10 progenies belonged to the experimental population and were assigned phenotypes and marker genotypes and 5 belonged to the selection population, only known on their marker genotypes. A total of 10,000 SNPs carried by 5 chromosomes of 1 Morgan each were simulated. Eight QTL were created (1 quadri-allelic, 2 linked in phase, 2 linked in repulsion, 1 imprinted and 2 epistatic). Random noise was added giving an heritability of 0.30. The marker density, LD and MAF were similar to real life parameters.

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