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Comparison of linear mixed model analysis and genealogy-based haplotype clustering with a Bayesian approach for association mapping in a pedigreed population

BACKGROUND: Despite many success stories of genome wide association studies (GWAS), challenges exist in QTL detection especially in datasets with many levels of relatedness. In this study we compared four methods of GWA on a dataset simulated for the 15(th )QTL-MAS workshop. The four methods were 1)...

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Detalles Bibliográficos
Autores principales: Dashab, Golam R, Kadri, Naveen K, Shariati, Mohammad M, Sahana, Goutam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3363158/
https://www.ncbi.nlm.nih.gov/pubmed/22640641
http://dx.doi.org/10.1186/1753-6561-6-S2-S4