Cargando…

Molecular targets for PDE inhibitor-mediated improvement of cardiac dysfunction in the mdx mouse?

Detalles Bibliográficos
Autores principales:	Adamo, Candace M, Dai, Dao-Fu, Percival, Justin M, Minami, Elina, Willis, Monte S, Patrucco, Enrico, Rybalkin, Sergei D, Froehner, Stanley C, Beavo, Joseph A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Oral Presentation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3363178/ http://dx.doi.org/10.1186/1471-2210-11-S1-O20

Ejemplares similares

Differential effects of PDE5 inhibitors on cardiac dysfunction in the MDX ouse model of Duchenne muscular dystrophy
por: Rybalkin, Sergei D, et al.
Publicado: (2013)

cGMP kinase I, cardiac hypertrophy and PDE inhibition
por: Patrucco, Enrico, et al.
Publicado: (2011)

Sildenafil ameliorates cardiomyopathy in dystrophin-null (mdx) mice
por: Parchen, Candace M, et al.
Publicado: (2009)

Calcium/Calpain mediated regulation of cyclic nucleotide phosphodiesterases, PDE3A and PDE5, in human platelets
por: Rybalkina, Irina G, et al.
Publicado: (2011)

Luteinizing Hormone Causes Phosphorylation and Activation of the cGMP Phosphodiesterase PDE5 in Rat Ovarian Follicles, Contributing, Together with PDE1 Activity, to the Resumption of Meiosis
por: Egbert, Jeremy R., et al.
Publicado: (2016)

A Yeast-Based Chemical Screen Identifies a PDE Inhibitor That Elevates Steroidogenesis in Mouse Leydig Cells via PDE8 and PDE4 Inhibition
por: Demirbas, Didem, et al.
Publicado: (2013)

CTLA-4 based therapy (MDX-010)
por: Korman, A
Publicado: (2003)

Skeletal Muscle NADPH Oxidase Is Increased and Triggers Stretch-Induced Damage in the mdx Mouse
por: Whitehead, Nicholas P., et al.
Publicado: (2010)

Cyclic nucleotide phosphodiesterases – 40 years of progress
por: Beavo, Joseph A, et al.
Publicado: (2009)

Benefits of PDE5 inhibition in patients with diastolic heart failure
por: Guazzi, Marco
Publicado: (2011)

Novel mechanisms of anti-hypertrophic effects from PDE5A inhibition
por: Kass, David A, et al.
Publicado: (2009)

cGMP kinase: past, presence and future
por: Hofmann, Franz, et al.
Publicado: (2013)

Functional Deficits in nNOSμ-Deficient Skeletal Muscle: Myopathy in nNOS Knockout Mice
por: Percival, Justin M., et al.
Publicado: (2008)

cGMP-Prkg1 signaling PDE5 inhibition shelter cochlear hair cells and hearing function
por: Knipper, Marlies, et al.
Publicado: (2013)

Dysfunctional Muscle and Liver Glycogen Metabolism in mdx Dystrophic Mice
por: Stapleton, David I., et al.
Publicado: (2014)

Chronic Dosing with Membrane Sealant Poloxamer 188 NF Improves Respiratory Dysfunction in Dystrophic Mdx and Mdx/Utrophin(-/-) Mice
por: Markham, Bruce E., et al.
Publicado: (2015)

Polymorphism in HIV-1 dependency factor PDE8A affects gene expression and HIV-1 replication in primary macrophages
por: Booiman, Thijs, et al.
Publicado: (2011)

Investigating the Potential for Sulforaphane to Attenuate Gastrointestinal Dysfunction in mdx Dystrophic Mice
por: Swiderski, Kristy, et al.
Publicado: (2021)

Roles of PDE1 in Pathological Cardiac Remodeling and Dysfunction
por: Chen, Si, et al.
Publicado: (2018)

Mitochondrial Dysfunction Is an Early Consequence of Partial or Complete Dystrophin Loss in mdx Mice
por: Moore, Timothy M., et al.
Publicado: (2020)

Activation of PDE10 and PDE11
por: Jäger, Ronald, et al.
Publicado: (2011)

Fast Track to MDX
por: Whitehorn, Mark, et al.
Publicado: (2005)

Dr. Bang-Ping Jiann: PDE5 inhibitors in erectile dysfunction
por: Gao, Lucine M.
Publicado: (2016)

A combined phase I/IIa study of the safety, bronchodilator and bronchoprotective effects of nebulized RPL554, a dual PDE3/4-inhibitor, in healthy subjects and asthmatics
por: Franciosi, Luigi, et al.
Publicado: (2013)

A comparison of the bone and growth phenotype of mdx, mdx:Cmah(−/−) and mdx:Utrn(+/−) murine models with the C57BL/10 wild-type mouse
por: Wood, Claire L., et al.
Publicado: (2020)

In vivo MRI Characterization of Progressive Cardiac Dysfunction in the mdx Mouse Model of Muscular Dystrophy
por: Stuckey, Daniel J., et al.
Publicado: (2012)

Intracavernosal injections in the diagnosis and treatment of PDE–5 resistant erectile dysfunction
por: Jakubczyk, Tomasz
Publicado: (2013)

AB233. PDE5-Is for erectile dysfunction in patients with multiple sclerosis
por: Yang, Xingliang, et al.
Publicado: (2016)

Computational Study on Selective PDE9 Inhibitors on PDE9-Mg/Mg, PDE9-Zn/Mg, and PDE9-Zn/Zn Systems
por: Sivakumar, Dakshinamurthy, et al.
Publicado: (2021)

Synthesising participants’ accounts from different mental health trials: the stride study
por: Turner, Katrina, et al.
Publicado: (2015)

Differential Expression and Function of PDE8 and PDE4 in Effector T cells: Implications for PDE8 as a Drug Target in Inflammation
por: Vang, Amanda G., et al.
Publicado: (2016)

cGMP-dependent kinase 2, Na(+)/H(+) regulatory factor 2, and Na(+)/H(+) exchanger isoform 3 assemble within lipid rafts in murine small intestinal brush border membrane
por: Luo, Min, et al.
Publicado: (2013)

Mutation Types and Aging Differently Affect Revertant Fiber Expansion in Dystrophic Mdx and Mdx52 Mice
por: Echigoya, Yusuke, et al.
Publicado: (2013)

Cognitive impairment appears progressive in the mdx mouse
por: Bagdatlioglu, Emine, et al.
Publicado: (2020)

Efficacy and safety of PDE5 inhibitors in the treatment of diabetes mellitus erectile dysfunction: Protocol for a systematic review
por: Li, Xiao, et al.
Publicado: (2018)

Novel variants in PDE6A and PDE6B genes and its phenotypes in patients with retinitis pigmentosa in Chinese families
por: Li, Yuyu, et al.
Publicado: (2022)

Geometric methods in PDE’s
por: Citti, Giovanna, et al.
Publicado: (2015)

Optimization with PDE constraints
por: Pinnau, Rene, et al.
Publicado: (2008)

PDE3 is the major cGMP-PDE in adult mouse ventricular cardiomyocytes
por: Götz, Konrad R, et al.
Publicado: (2013)

Investigation of PDE5/PDE6 and PDE5/PDE11 selective potent tadalafil-like PDE5 inhibitors using combination of molecular modeling approaches, molecular fingerprint-based virtual screening protocols and structure-based pharmacophore development
por: Kayık, Gülru, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_c6kaif7jftistj7cat4bdtvp65