Cargando…

Insufficient autophagy relates to mitochondrial dysfunction, organ failure and adverse outcome in an animal model of critical illness

Detalles Bibliográficos
Autores principales:	Gunst, J, Derese, I, Aertgeerts, A, Ververs, EJ, Wauters, A, Van den Berghe, G, Vanhorebeek, I
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Poster Presentation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3363429/ http://dx.doi.org/10.1186/cc10618

Ejemplares similares

Fibroblast growth factor 21 response to critical illness: effect of blood glucose control and relation with mitochondrial dysfunction, the integrated stress response and survival
por: Thiessen, S, et al.
Publicado: (2015)

Insufficient activation of autophagy allows accumulation of cellular damage and may contribute to sustained organ failure in prolonged critically ill patients
por: Gunst, J, et al.
Publicado: (2011)

Impact of early versus late parenteral nutrition on morphological and molecular markers of atrophy and autophagy in skeletal muscle of critically ill patients
por: Vanhorebeek, I, et al.
Publicado: (2013)

Persisting neuroendocrine abnormalities and their association with physical impairment 5 years after critical illness
por: Vanhorebeek, Ilse, et al.
Publicado: (2021)

Hepatic mitochondrial dysfunction in fluid-resuscitated porcine septic shock
por: Wauters, J, et al.
Publicado: (2007)

Nutrition and autophagy deficiency in critical illness
por: Vanhorebeek, Ilse, et al.
Publicado: (2023)

Receptor for advanced glycation end products axis in critically ill patients
por: Ingels, C, et al.
Publicado: (2014)

Critical Illness–induced Corticosteroid Insufficiency: What It Is Not and What It Could Be
por: Téblick, Arno, et al.
Publicado: (2022)

Effect of increasing intravenous glucose load in the presence of normoglycemia on outcome and metabolism in critically ill rabbits
por: Derde, S, et al.
Publicado: (2009)

The Role of Autophagy in Critical Illness-induced Liver Damage
por: Thiessen, Steven E., et al.
Publicado: (2017)

Skeletal Muscle Myokine Expression in Critical Illness, Association With Outcome and Impact of Therapeutic Interventions
por: Vanhorebeek, Ilse, et al.
Publicado: (2023)

The clinical potential of GDF15 as a “ready-to-feed indicator” for critically ill adults
por: Van Dyck, Lisa, et al.
Publicado: (2020)

Towards a fasting-mimicking diet for critically ill patients: the pilot randomized crossover ICU-FM-1 study
por: Van Dyck, Lisa, et al.
Publicado: (2020)

Organ dysfunction in critical illness: impact of maintaining normoglycemia and glycemia-independent insulin actions
por: Ellger, B, et al.
Publicado: (2006)

Aberrant bone metabolism in critical illness
por: Vanhees, I, et al.
Publicado: (2012)

Mechanisms of kidney protection by intensive insulin therapy during critical illness
por: Vanhorebeek, I, et al.
Publicado: (2008)

Strict blood glucose control with insulin improves hepatic mitochondrial ultrastructure and function in critical illness
por: Vanhorebeek, I, et al.
Publicado: (2004)

Effects of hyperglycemia and intensive insulin therapy on neurons and glial cells during critical illness
por: Sonneville, R, et al.
Publicado: (2011)

Early detection of acute kidney injury during the first week of the ICU
por: Flechet, M, et al.
Publicado: (2015)

SAT-155 Temporal Activation of the Unfolded Protein Response and Concomitant Downregulation of Key Hepatic Transcription Factors in Critical Illness
por: Vankrunkelsven, Wouter, et al.
Publicado: (2019)

OR17-1 Changes in the Hypothalamic-Pituitary-Adrenal Axis during Pediatric Critical Illness
por: Jacobs, An, et al.
Publicado: (2019)

Critical illness-induced bone loss is related to deficient autophagy and histone hypomethylation
por: Owen, Helen C, et al.
Publicado: (2015)

The association of hypoglycemia with outcome of critically ill children in relation to nutritional and blood glucose control strategies
por: Gunst, Jan, et al.
Publicado: (2023)

DNA methylation alterations in muscle of critically ill patients
por: Van Dyck, Lisa, et al.
Publicado: (2022)

Cortisol metabolism in critical illness: effects of intensive insulin therapy
por: Vanhorebeek, I, et al.
Publicado: (2005)

Early Supplemental Parenteral Nutrition in Critically Ill Children: An Update
por: Jacobs, An, et al.
Publicado: (2019)

Time course of altered DNA methylation evoked by critical illness and by early administration of parenteral nutrition in the paediatric ICU
por: Verlinden, Ines, et al.
Publicado: (2020)

Long-term impact of paediatric critical illness on the difference between epigenetic and chronological age in relation to physical growth
por: Verlinden, Ines, et al.
Publicado: (2023)

Abnormal DNA methylation within genes of the steroidogenesis pathway two years after paediatric critical illness and association with stunted growth in height further in time
por: Vanhorebeek, Ilse, et al.
Publicado: (2023)

Reduced cortisol metabolism drives hypercortisolism in critical illness
por: Boonen, E, et al.
Publicado: (2012)

Protection of mitochondria by intensive insulin therapy in critical illness: blood glucose control or insulin?
por: Vanhorebeek, I, et al.
Publicado: (2006)

Intensive insulin therapy and brief hypoglycemia do not increase neurological injury markers in critically ill children
por: Gielen, M, et al.
Publicado: (2010)

Targeted treatment of iron deficiency in prolonged critical illness: an opportunity to improve survival or not?
por: Gunst, Jan, et al.
Publicado: (2021)

Hyperglycemia and insulin resistance in COVID-19 versus non-COVID critical illness: Are they really different?
por: Langouche, Lies, et al.
Publicado: (2021)

THU155 Aberrant DNA Methylation Within Genes Of The HPA-axis Two Years After Paediatric Critical Illness, Role Of Glucocorticoid Treatment And Association With Impaired Physical And Neurocognitive Development.
por: Coppens, Gregoire, et al.
Publicado: (2023)

Assessment of aberrant DNA methylation two years after paediatric critical illness: a pre-planned secondary analysis of the international PEPaNIC trial
por: Coppens, Grégoire, et al.
Publicado: (2022)

Neurocognitive consequences of iatrogenicphthalate exposure during critical illness in children: a study of a development and validation cohort
por: Verstraete, S, et al.
Publicado: (2015)

The Hypothalamus-pituitary-adrenocortical Response to Critical Illness: A Concept in Need of Revision
por: Langouche, Lies, et al.
Publicado: (2023)

Development of muscle weakness in a mouse model of critical illness: does fibroblast growth factor 21 play a role?
por: Vankrunkelsven, Wouter, et al.
Publicado: (2023)

Recovery from critical illness-induced organ failure: the role of autophagy
por: Gunst, Jan
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_jthrstfu6popsfu9c9l8uhioc0