Cinacalcet HCl prevents development of parathyroid gland hyperplasia and reverses established parathyroid gland hyperplasia in a rodent model of CKD

BACKGROUND. Secondary hyperparathyroidism (sHPT) represents an adaptive response to progressively impaired control of calcium, phosphorus and vitamin D in chronic kidney disease (CKD). It is characterized by parathyroid hyperplasia and excessive synthesis and secretion of parathyroid hormone (PTH)....

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Detalles Bibliográficos
Autores principales: Miller, Gerald, Davis, James, Shatzen, Edward, Colloton, Matthew, Martin, David, Henley, Charles M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3363978/
https://www.ncbi.nlm.nih.gov/pubmed/22036941
http://dx.doi.org/10.1093/ndt/gfr589

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