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Protein-Losing Enteropathy in Ulcerative Colitis

Protein-losing enteropathy (PLE) is a debilitating potential complication of ulcerative colitis (UC). We report a case of PLE in a 26-year-old male patient with UC. The patient lost 50 pounds in the setting of a UC flare and was found to have an albumin level of 1.2 g/dl. Although the patient's...

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Autores principales: Ungaro, Ryan, Babyatsky, Mark W., Zhu, Hongfa, Freed, Jeffrey S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3364098/
https://www.ncbi.nlm.nih.gov/pubmed/22679407
http://dx.doi.org/10.1159/000338191
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author Ungaro, Ryan
Babyatsky, Mark W.
Zhu, Hongfa
Freed, Jeffrey S.
author_facet Ungaro, Ryan
Babyatsky, Mark W.
Zhu, Hongfa
Freed, Jeffrey S.
author_sort Ungaro, Ryan
collection PubMed
description Protein-losing enteropathy (PLE) is a debilitating potential complication of ulcerative colitis (UC). We report a case of PLE in a 26-year-old male patient with UC. The patient lost 50 pounds in the setting of a UC flare and was found to have an albumin level of 1.2 g/dl. Although the patient's UC was clinically controlled with steroids, the weight loss and hypoalbuminemia persisted with the patient's course complicated by development of deep vein thrombosis and pulmonary embolism. The diagnosis of PLE was confirmed with measurement of stool alpha-1-antitrypsin clearance. The patient's condition significantly improved following procto-colectomy.
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spelling pubmed-33640982012-06-07 Protein-Losing Enteropathy in Ulcerative Colitis Ungaro, Ryan Babyatsky, Mark W. Zhu, Hongfa Freed, Jeffrey S. Case Rep Gastroenterol Published online: April, 2012 Protein-losing enteropathy (PLE) is a debilitating potential complication of ulcerative colitis (UC). We report a case of PLE in a 26-year-old male patient with UC. The patient lost 50 pounds in the setting of a UC flare and was found to have an albumin level of 1.2 g/dl. Although the patient's UC was clinically controlled with steroids, the weight loss and hypoalbuminemia persisted with the patient's course complicated by development of deep vein thrombosis and pulmonary embolism. The diagnosis of PLE was confirmed with measurement of stool alpha-1-antitrypsin clearance. The patient's condition significantly improved following procto-colectomy. S. Karger AG 2012-04-11 /pmc/articles/PMC3364098/ /pubmed/22679407 http://dx.doi.org/10.1159/000338191 Text en Copyright © 2012 by S. Karger AG, Basel http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-Noncommercial-No-Derivative-Works License (http://creativecommons.org/licenses/by-nc-nd/3.0/). Users may download, print and share this work on the Internet for noncommercial purposes only, provided the original work is properly cited, and a link to the original work on http://www.karger.com and the terms of this license are included in any shared versions.
spellingShingle Published online: April, 2012
Ungaro, Ryan
Babyatsky, Mark W.
Zhu, Hongfa
Freed, Jeffrey S.
Protein-Losing Enteropathy in Ulcerative Colitis
title Protein-Losing Enteropathy in Ulcerative Colitis
title_full Protein-Losing Enteropathy in Ulcerative Colitis
title_fullStr Protein-Losing Enteropathy in Ulcerative Colitis
title_full_unstemmed Protein-Losing Enteropathy in Ulcerative Colitis
title_short Protein-Losing Enteropathy in Ulcerative Colitis
title_sort protein-losing enteropathy in ulcerative colitis
topic Published online: April, 2012
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3364098/
https://www.ncbi.nlm.nih.gov/pubmed/22679407
http://dx.doi.org/10.1159/000338191
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