An interdomain binding site on HIV-1 Nef interacts with PACS-1 and PACS-2 on endosomes to down-regulate MHC-I

The human immunodeficiency virus type 1 (HIV-1) accessory protein Nef directs virus escape from immune surveillance by subverting host cell intracellular signaling and membrane traffic to down-regulate cell-surface major histocompatibility complex class I (MHC-I). The interaction of Nef with the sor...

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Detalles Bibliográficos
Autores principales: Dikeakos, Jimmy D., Thomas, Laurel, Kwon, Grace, Elferich, Johannes, Shinde, Ujwal, Thomas, Gary
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2012
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3364181/
https://www.ncbi.nlm.nih.gov/pubmed/22496420
http://dx.doi.org/10.1091/mbc.E11-11-0928

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3364181/
https://www.ncbi.nlm.nih.gov/pubmed/22496420
http://dx.doi.org/10.1091/mbc.E11-11-0928

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