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FOXO3/FKHRL1 is activated by 5-aza-2-deoxycytidine and induces silenced caspase-8 in neuroblastoma
Forkhead box O (FOXO) transcription factors control diverse cellular functions, such as cell death, metabolism, and longevity. We analyzed FOXO3/FKHRL1 expression and subcellular localization in tumor sections of neuroblastoma patients and observed a correlation between nuclear FOXO3 and high caspas...
Autores principales: | Geiger, Kathrin, Hagenbuchner, Judith, Rupp, Martina, Fiegl, Heidi, Sergi, Consolato, Meister, Bernhard, Kiechl-Kohlendorfer, Ursula, Müller, Thomas, Ausserlechner, Michael J., Obexer, Petra |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3364184/ https://www.ncbi.nlm.nih.gov/pubmed/22493319 http://dx.doi.org/10.1091/mbc.E11-06-0535 |
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