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FOX-2 Dependent Splicing of Ataxin-2 Transcript Is Affected by Ataxin-1 Overexpression
Alternative splicing is a fundamental posttranscriptional mechanism for controlling gene expression, and splicing defects have been linked to various human disorders. The splicing factor FOX-2 is part of a main protein interaction hub in a network related to human inherited ataxias, however, its imp...
Autores principales: | Welzel, Franziska, Kaehler, Christian, Isau, Melanie, Hallen, Linda, Lehrach, Hans, Krobitsch, Sylvia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3364202/ https://www.ncbi.nlm.nih.gov/pubmed/22666429 http://dx.doi.org/10.1371/journal.pone.0037985 |
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