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Transcriptional Activation of Low-Density Lipoprotein Receptor Gene by DJ-1 and Effect of DJ-1 on Cholesterol Homeostasis

DJ-1 is a novel oncogene and also causative gene for familial Parkinson’s disease park7. DJ-1 has multiple functions that include transcriptional regulation, anti-oxidative reaction and chaperone and mitochondrial regulation. For transcriptional regulation, DJ-1 acts as a coactivator that binds to v...

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Detalles Bibliográficos
Autores principales: Yamaguchi, Shiori, Yamane, Takuya, Takahashi-Niki, Kazuko, Kato, Izumi, Niki, Takeshi, Goldberg, Matthew S., Shen, Jie, Ishimoto, Kenji, Doi, Takefumi, Iguchi-Ariga, Sanae M. M., Ariga, Hiroyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3364227/
https://www.ncbi.nlm.nih.gov/pubmed/22666465
http://dx.doi.org/10.1371/journal.pone.0038144