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Beyond Repair Foci: DNA Double-Strand Break Repair in Euchromatic and Heterochromatic Compartments Analyzed by Transmission Electron Microscopy

PURPOSE: DNA double-strand breaks (DSBs) generated by ionizing radiation pose a serious threat to the preservation of genetic and epigenetic information. The known importance of local chromatin configuration in DSB repair raises the question of whether breaks in different chromatin environments are...

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Detalles Bibliográficos
Autores principales:	Lorat, Yvonne, Schanz, Stefanie, Schuler, Nadine, Wennemuth, Gunther, Rübe, Christian, Rübe, Claudia E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3364237/ https://www.ncbi.nlm.nih.gov/pubmed/22666473 http://dx.doi.org/10.1371/journal.pone.0038165

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