Cargando…

Breast Cancer 1 (BrCa1) May Be behind Decreased Lipogenesis in Adipose Tissue from Obese Subjects

CONTEXT: Expression and activity of the main lipogenic enzymes is paradoxically decreased in obesity, but the mechanisms behind these findings are poorly known. Breast Cancer 1 (BrCa1) interacts with acetyl-CoA carboxylase (ACC) reducing the rate of fatty acid biosynthesis. In this study, we aimed t...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ortega, Francisco J., Moreno-Navarrete, José M., Mayas, Dolores, García-Santos, Eva, Gómez-Serrano, María, Rodriguez-Hermosa, José I., Ruiz, Bartomeu, Ricart, Wifredo, Tinahones, Francisco J., Frühbeck, Gema, Peral, Belen, Fernández-Real, José M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3364252/ https://www.ncbi.nlm.nih.gov/pubmed/22666314 http://dx.doi.org/10.1371/journal.pone.0033233

Ejemplares similares

The MRC1/CD68 Ratio Is Positively Associated with Adipose Tissue Lipogenesis and with Muscle Mitochondrial Gene Expression in Humans
por: Moreno-Navarrete, José María, et al.
Publicado: (2013)

Study of caveolin-1 gene expression in whole adipose tissue and its subfractions and during differentiation of human adipocytes
por: Fernández-Real, José M, et al.
Publicado: (2010)

MiRNA Expression Profile of Human Subcutaneous Adipose and during Adipocyte Differentiation
por: Ortega, Francisco J., et al.
Publicado: (2010)

Circulating omentin concentration increases after weight loss
por: Moreno-Navarrete, José María, et al.
Publicado: (2010)

OCT1 Expression in Adipocytes Could Contribute to Increased Metformin Action in Obese Subjects
por: Moreno-Navarrete, José María, et al.
Publicado: (2011)

Serum HER-2 concentration is associated with insulin resistance and decreases after weight loss
por: Fernández-Real, José Manuel, et al.
Publicado: (2010)

Increased adipose tissue heme levels and exportation are associated with altered systemic glucose metabolism
por: Moreno-Navarrete, José María, et al.
Publicado: (2017)

Rab18 Dynamics in Adipocytes in Relation to Lipogenesis, Lipolysis and Obesity
por: Pulido, Marina R., et al.
Publicado: (2011)

Circulating Zonulin, a Marker of Intestinal Permeability, Is Increased in Association with Obesity-Associated Insulin Resistance
por: Moreno-Navarrete, José María, et al.
Publicado: (2012)

Complement Factor H Is Expressed in Adipose Tissue in Association With Insulin Resistance
por: Moreno-Navarrete, José María, et al.
Publicado: (2010)

Iron and Obesity Status-Associated Insulin Resistance Influence Circulating Fibroblast-Growth Factor-23 Concentrations
por: Fernández-Real, José Manuel, et al.
Publicado: (2013)

Extracellular Fatty Acid Synthase: A Possible Surrogate Biomarker of Insulin Resistance
por: Fernandez-Real, Jose Manuel, et al.
Publicado: (2010)

Lactoferrin gene knockdown leads to similar effects to iron chelation in human adipocytes
por: Moreno-Navarrete, José María, et al.
Publicado: (2014)

Downregulation of hepatic lipopolysaccharide binding protein improves lipogenesis-induced liver lipid accumulation
por: Latorre, Jessica, et al.
Publicado: (2022)

Circulating Tryptase as a Marker for Subclinical Atherosclerosis in Obese Subjects
por: Moreno, María, et al.
Publicado: (2014)

Multiple Hürthle cell adenomas in a patient with thyroid hormone resistance
por: Xifra, Gemma, et al.
Publicado: (2013)

Uncovering Suitable Reference Proteins for Expression Studies in Human Adipose Tissue with Relevance to Obesity
por: Pérez-Pérez, Rafael, et al.
Publicado: (2012)

Permanent cystathionine-β-Synthase gene knockdown promotes inflammation and oxidative stress in immortalized human adipose-derived mesenchymal stem cells, enhancing their adipogenic capacity
por: Comas, Ferran, et al.
Publicado: (2020)

Circulating Retinol-Binding Protein-4 Concentration Might Reflect Insulin Resistance–Associated Iron Overload
por: Fernández-Real, José Manuel, et al.
Publicado: (2008)

Inflammation triggers specific microRNA profiles in human adipocytes and macrophages and in their supernatants
por: Ortega, Francisco José, et al.
Publicado: (2015)

Adipocytokines and Insulin Resistance: The possible role of lipocalin-2, retinol binding protein-4, and adiponectin
por: Esteve, Eduardo, et al.
Publicado: (2009)

Surfactant Protein D, a Marker of Lung Innate Immunity, Is Positively Associated With Insulin Sensitivity
por: Fernández-Real, José Manuel, et al.
Publicado: (2010)

Decreased RB1 mRNA, Protein, and Activity Reflect Obesity-Induced Altered Adipogenic Capacity in Human Adipose Tissue
por: Moreno-Navarrete, José María, et al.
Publicado: (2013)

Hypoxia is associated with a lower expression of genes involved in lipogenesis in visceral adipose tissue
por: García-Fuentes, Eduardo, et al.
Publicado: (2015)

Circulating Irisin Levels Are Positively Associated with Metabolic Risk Factors in Sedentary Subjects
por: Moreno, María, et al.
Publicado: (2015)

Neuregulin 4 Is a Novel Marker of Beige Adipocyte Precursor Cells in Human Adipose Tissue
por: Comas, Ferran, et al.
Publicado: (2019)

Inverse relation between FASN expression in human adipose tissue and the insulin resistance level
por: Mayas, María D, et al.
Publicado: (2010)

Low serum mannose-binding lectin are associated with inflammation, new-onset diabetes mellitus and subclinical rejection after renal transplantation
por: Moreso, Francesc, et al.
Publicado: (2011)

Platelet count and Interleukin 6 Gene polymorphism in healthy subjects
por: Fernandez-Real, José-Manuel, et al.
Publicado: (2001)

Circulating Irisin and Myostatin as Markers of Muscle Strength and Physical Condition in Elderly Subjects
por: Planella-Farrugia, Cristina, et al.
Publicado: (2019)

Serum neuregulin 4 is negatively correlated with insulin sensitivity in humans and impairs mitochondrial respiration in HepG2 cells
por: Martínez, Cristina, et al.
Publicado: (2022)

Specific adipose tissue Lbp gene knockdown prevents diet-induced body weight gain, impacting fat accretion-related gene and protein expression
por: Latorre, Jessica, et al.
Publicado: (2022)

Neuregulin 4 Downregulation Induces Insulin Resistance in 3T3-L1 Adipocytes through Inflammation and Autophagic Degradation of GLUT4 Vesicles
por: Díaz-Sáez, Francisco, et al.
Publicado: (2021)

Common Genetic Variants of Surfactant Protein-D (SP-D) Are Associated with Type 2 Diabetes
por: Pueyo, Neus, et al.
Publicado: (2013)

Progression from High Insulin Resistance to Type 2 Diabetes Does Not Entail Additional Visceral Adipose Tissue Inflammation
por: Barbarroja, Nuria, et al.
Publicado: (2012)

Acylated and desacyl ghrelin are associated with hepatic lipogenesis, β-oxidation and autophagy: role in NAFLD amelioration after sleeve gastrectomy in obese rats
por: Ezquerro, Silvia, et al.
Publicado: (2016)

Olfaction in eating disorders and abnormal eating behavior: a systematic review
por: Islam, Mohammed A., et al.
Publicado: (2015)

Erratum to: The gut microbiota profile is associated with insulin action in humans
por: Serino, Matteo, et al.
Publicado: (2012)

The gut microbiota profile is associated with insulin action in humans
por: Serino, Matteo, et al.
Publicado: (2012)

Caspase Induction and BCL2 Inhibition in Human Adipose Tissue: A potential relationship with insulin signaling alteration
por: Tinahones, Francisco José, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_c6nrr96j1odhot57rtt564bs8c