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A Systematic Prediction of Multiple Drug-Target Interactions from Chemical, Genomic, and Pharmacological Data

In silico prediction of drug-target interactions from heterogeneous biological data can advance our system-level search for drug molecules and therapeutic targets, which efforts have not yet reached full fruition. In this work, we report a systematic approach that efficiently integrates the chemical...

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Detalles Bibliográficos
Autores principales: Yu, Hua, Chen, Jianxin, Xu, Xue, Li, Yan, Zhao, Huihui, Fang, Yupeng, Li, Xiuxiu, Zhou, Wei, Wang, Wei, Wang, Yonghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3364341/
https://www.ncbi.nlm.nih.gov/pubmed/22666371
http://dx.doi.org/10.1371/journal.pone.0037608